| reverse transcriptase inhibitors | Inhibitors of reverse transcriptase (RNA-directed DNA polymerase), an enzyme that synthesises DNA on an RNA template. (12 Dec 1998) |
|---|---|
| reverse transcriptase md | <molecular biology> A viral enzyme that constructs DNA from an RNA template, which is an essential step in the life-cycle of a retrovirus such as HIV (09 Oct 1997) |
| reverse transcriptase PCR | A technique used to amplify RNA targets. The specimen containing the target RNA (e.g., HIV-1 RNA, Hepatitis C Virus RNA) is subjected to reverse transcription to make complementary DNA (cDNA), which is then, in turn, amplified by PCR. Acronym: RT-PCR (05 Mar 2000) |
| reverse transcription | <molecular biology> The process of copying information found in RNA into DNA. (09 Oct 1997) |
| reverse transcriptons | An enzyme that converts RNA to DNA. Some viruses have only RNA as their primary genetic material. By converting their RNA genes to DNA with this enzyme, the host cell is 'tricked' into creating new copies of the virus. Useful in genetic engineering to make DNA from mRNA. (14 Nov 1997) |
| reverse Trendelenburg position | Supine position without flexing or extending, in which the head is higher than the feet. (05 Mar 2000) |
| HIV-1 reverse transcriptase | <enzyme> HIV-1 enzyme responsible for the synthesis of DNA from genomic RNA of the virus. It is encoded by the pol gene of HIV-1. Registry number: EC 2.7.7.- (12 Dec 1998) |
| HIV-2 reverse transcriptase | <enzyme> Responsible for synthesis of double-stranded DNA from the genomic RNA of the virus; has rnase h and DNA-dependent DNA polymerase activities; was indexed as reverse transcriptase (87-91) Registry number: EC 2.7.7.- (26 Jun 1999) |
| DNA reverse gyrase | <enzyme> A topoisomerase II subclass which introduces positive superhelical turns into DNA Registry number: EC 3.1.- Synonym: reverse gyrase (26 Jun 1999) |
| triiodothyronine, reverse | <chemical> 0-(4-hydroxy-3,5-diiodophenyl)-3-iodo-l-tyrosine. A metabolite of thyroxine formed by the peripheral degradation of thyroxine as a result of the tyrosyl or inner ring 5-deiodination. In systemic disease states or in neonates, levels of triiodothyronine are low and those of reverse triiodothyronine are elevated. Reverse t3 is therefore useful as a diagnostic aid and in the treatment of foetal and infantile hypothyroidism. Chemical name: L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo- (12 Dec 1998) |
| Aaron's sign | <clinical sign> In acute appendicitis, a referred pain or feeling of distress in the epigastrium or precordial region on continuous firm pressure over McBurney's point. (05 Mar 2000) |
| Abadie's sign of tabes dorsalis | Insensibility to pressure over the tendo achillis. (05 Mar 2000) |
| Abrahams' sign | <clinical sign> An obsolete sign: Rales and other adventitious sounds, changes in the respiratory murmurs, and increase in the whispered sound can be heard on auscultation over the acromial end of the clavicle some time before they become audible at the apex; heard primarily in pulmonary tuberculosis affecting the apical portion of the lung, a dull-flat note, i.e., one between the normal dullness at the right apex and absolute flatness, heard on percussion in that region, indicating progress from incipient to advanced tuberculosis. (05 Mar 2000) |
| accessory sign | <clinical sign> A finding frequently but not consistently present in a disease. Synonym: assident sign. (05 Mar 2000) |
| Allis' sign | <clinical sign> In fracture of the neck of the femur, the trochanter rides up, relaxing the fascia lata, so that the finger can be sunk deeply between the great trochanter and the iliac crest. (05 Mar 2000) |