| RFLPs | Restriction Fragment Length Polymorphisms; 제한효소단편장다형 |
|---|---|
| FR | failure rate; film-screen radiograph; fasciculus retroflexus; febrile reaction; feedback regulation;... |
| RE | radium emanation; readmission; rectal examination; reference emitter; reflux esophagitis; regional e... |
| RELP | restriction fragment length polymorphism |
| RELV | restriction fragment length variant |
| DNA restriction enzymes | <enzyme> Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of dnas, and have made it possible to splice and recombine genes from one organism into the genome of another. Registry number: EC 3.1.21 (12 Dec 1998) |
|---|---|
| DNA restriction-modification enzymes | Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage. (12 Dec 1998) |
| ecori restriction enzyme | <enzyme, molecular biology> A commonly-used restriction enzyme (enzyme which will cleave the phosphodiester bonds of DNA at specific nucleotide sequences) that came from the bacteria Escherichia coli and recognises the sequence GAATTC. The enzyme will make a staggered cut of the double-stranded DNA molecule by cutting between the G and A on both strands. (09 Oct 1997) |
| lactase restriction | An inherited trait in which there is low lactase activity and thus there is defective lactose intestinal metabolism. Compare: lactase persistence. (05 Mar 2000) |
| macrorestriction map | <molecular biology> Map depicting the order of and distance between sites at which restriction enzymes cleave chromosomes. (09 Oct 1997) |
| map | 1. A representation of the surface of the earth, or of some portion of it, showing the relative position of the parts represented; usually on a flat surface. Also, such a representation of the celestial sphere, or of some part of it. There are five principal kinds of projection used in making maps: the orthographic, the stereographic, the globuar, the conical, and the cylindrical, or Mercator's projection. See Projection. 2. Anything which represents graphically a succession of events, states, or acts; as, an historical map. "Thus is his cheek the map of days outworn. <botany>" (Shak) Map lichen, a lichen (Lecidea geographica) growing on stones in curious maplike figures. Origin: From F. Mappe, in mappemonde map of the world, fr. L. Mappa napkin, signal cloth; a Punic word. Cf. Apron, Napkin, Nappe. Source: Websters Dictionary (01 Mar 1998) |
| map, contig | A map depicting the relative order of a linked library of small overlapping clones representing a complete chromosome segment. (12 Dec 1998) |
| map distance | The degree of separation of two loci on a linkage map, measured in morgans or centimorgans. (05 Mar 2000) |
| map-dot-fingerprint dystrophy | Fingerprint dystrophy accompanied by map-like patterns and microcystic epithelial inclusions. (05 Mar 2000) |
| MAP kinase | Mitogen activated protein kinases. (ERKs: externally regulated kinases) Serine threonine kinases that are activated when quiescent cells are treated with mitogens and therefore potentially transmit signal for entry into cell cycle. One target is trancription factor p62TCF. MAP kinase itself can be phosphorylated by MAP kinase kinase and this may in turn be controlled by RAF 1. Confusingly, do phosphorylate microtubule-associated proteins. (18 Nov 1997) |
| MAP kinase kinase kinase | <enzyme> From pc12 cells; reactivates map kinase kinase inactivated by protein phosphatase 2a by phosphorylation of serine residues; tak1 (tgf-beta-activated kinase 1) is a member of the mapkkk family; genbank ab006787 (mouse) Registry number: EC 2.7.10.- Synonym: mapkkk, tak1 mapkkk, ask1 (kinase), apoptosis signal-regulating kinase 1 (26 Jun 1999) |
| map, linkage | A map of the genes on a chromosome based on linkage analysis. A linkage map does not show the physical distances between genes but rather their relative positions, as determined by how often two gene loci are inherited together. The closer two genes are (the more tightly they are linked), the more often they will be inherited together. Linkage distance is measured in centimorgans (cm). (12 Dec 1998) |
| map, physical | A map of the locations of identifiable landmarks on chromosomes. Physical distance is measured in base pairs. The physical map differs from the genetic map which is based purely on genetic linkage data. In the human genome, the lowest-resolution physical map is the banding patterns of the 24 different chromosomes. The highest-resolution physical map is the complete nucleotide sequence of all chromosomes, a future goal. (12 Dec 1998) |
| genetic map | <genetics> A map of the relative positions of genetic loci on a chromosome, determined onthe basis of how often the loci are inherited together. Distance ismeasured in centimorgans (cM). (09 Oct 1997) |
| peptide map | Proteases will produce fragments of a characteristic size from a protein and this can be used as a test for the identity or otherwise of two similar sized proteins. It is possible to produce a peptide fragment map from a single gel band. (18 Nov 1997) |
| restriction map |
A diagram that shows restriction sites (ie, where a restriction enzyme cleaves DNA) in relation to one another.
출처: www.ncbiotech.org/biotech101/glossary.cfm
|
|---|---|
| restriction map |
A physical map or depiction of a gene (or genome) derived by ordering overlapping restriction fragments produced by digestion of the DNA with a number of restriction enzymes.
출처: lomiweb.med.auth.gr/xml_output/bioglossary/R_gloss...
|