| 영문 | iron deficiency anemia | 한글 | 철결핍빈혈 |
|---|---|---|---|
| 설명 | 적혈구의 기능은 산소를 운반하는데 있다. 적혈구 속에 산소와 결합을 하여 산소를 운반하는 혈색소라는 물질이 있다. 철은 이 혈색소의 중요한 부분을 이루는 것으로 철이 없으면 혈색소가 만들어질 수가 없다. 혈색소가 없으면 역시 적혈구도 만들어지지 않으므로 체내에 철이 부족하면 빈혈이 생긴다. 이 철결핍성 빈혈은 빈혈의 원인 중에서 가장 흔한 것이다(약 25%를 차지한다). 철저장량의 저하-결핍, 혈청철농도의 저하, 트란스페린량 상승, 트란스페린포화도의 저하, 혈색소농도 또는 헤마토크리트의 저하, 저색소성대적혈구를 특징으로 하는 빈혈로서, 생체 내에서 철이 장기에 걸쳐 결핍되며 그 때문에 혈색소 생산 감소에 의해 일어난다. 창자에서의 철흡수량 부족, 철의 수요 증대(유아기, 사춘기, 임신), 철소실과잉(출혈)에 의해 일어나며, 특히 사춘기에서 폐경기까지의 여성에게 많다. 증상으로서는 얼굴창백, 피로감, 피부창백, 손톱 변화(스푼 모양) 등을 나타낸다. 구강 영역에서는 혀의 접촉통, 발적, 건조감, 삼킴곤란을 수반하면 플러머-빈슨(Plummer-Vinson)증후군이라고 한다. 혈액 소견은 혈청철은 저하하며, 철결합능력의 상승, 저색소성 작은적혈구성을 나타낸다. |
||
| RA | 1) Refractory Anemia 2) Rheumatoid Arthritis ? Arthritis 3... |
|---|---|
| RAEB | Refractory Anemia with Excess of Blasts |
| RAEB-T | Refractory Anemia with Excess Blasts in Transformation |
| RARS | Refractory Anemia with Ringed Sideroblast = AISA |
| IARSA | idiopathic acquired refractory sideroblastic anemia |
| refractory anaemia with excess blasts | <haematology> A form of myelodysplasia characterised by the build up of immature white blood cells (blasts) in the bone marrow. If the immature cells are particularly numerous it may indicate a chance of transformation to acute leukaemia and the condition is called refractory anaemia with excess blasts in transformation (RAEBt). Acronym: RAEB (13 Nov 1997) |
|---|---|
| refractory cast | A cast made of material that will withstand the high temperatures of metal casting or soldering without disintegrating. Synonym: investment cast. (05 Mar 2000) |
| refractory flask | A metal tube in which a refractory mold is made for casting metal dental restorations or appliances. Synonym: casting flask, casting ring. (05 Mar 2000) |
| refractory lining | A lining, usually of ceramic, capable of resisting and maintaining high temperatures. (05 Dec 1998) |
| refractory period | <neurology, physiology> most commonly used in reference to the interval (typically 1ms) after the passage of an action potential during which an axon is incapable of responding to another. This is caused by inactivation of the sodium channels after opening. The maximum frequency at which neurons can fire is thus limited to a few hundred Hertz. An analogous refractory period occurs in individuals of Dictyostelium discoideum, which are insensitive to extracellular cyclic AMP immediately after a pulse of cAMP has been secreted. The term can be applied to any system where a similar insensitive period follows stimulation. (18 Nov 1997) |
| refractory period of electronic pacemaker | The time required to restore full sensitivity after detecting cardiac activity or delivering a pacing impulse. (05 Mar 2000) |
| refractory period, psychological | A delayed response interval occurring when two stimuli are presented in close succession. (12 Dec 1998) |
| refractory rickets | Rickets that does not respond to treatment with usual doses of vitamin D and adequate dietary calcium and phosphorus. Most often due to inherited renal tubular disorder e.g., Fanconi syndrome. Renal rickets, a form of rickets occurring in children in association with and apparently caused by renal disease with hyperphosphatemia. Synonym: pseudorickets, renal fibrocystic osteosis, renal infantilism, renal osteitis fibrosa. (05 Mar 2000) |
| refractory state | Subnormal excitability immediately following a response to previous excitation; the state is divided into absolute and relative phases. (05 Mar 2000) |
| relative refractory period | The period between the effective refractory period and the end of the refractory period; fibres then respond only to high intensity stimuli and the impulses conduct more slowly than normally. (05 Mar 2000) |
| primary refractory anaemia | Any of a group of anaemic conditions in which there is persistent, frequently advanced anaemia that is not successfully treated by any means except blood transfusions, and that is not associated with another primary disease. (05 Mar 2000) |
| secondary refractory anaemia | Any persistent anaemia that is successfully treated only by blood transfusions, and that is associated with another condition. (05 Mar 2000) |
| effective refractory period | The period during which impulses may appear but are too weak to be conducted; the longest interval between adequate stimuli, falling just short of the time necessary to allow a propagated response to be evoked in a tissue by the second stimulus; it differs from the functional refractory period in that it is a measure of stimulus interval rather than response interval of time. (05 Mar 2000) |
| total refractory period | The absolute refractory period plus the relative refractory period. (05 Mar 2000) |
| functional refractory period | The minimum interval possible between successive responses to stimulation of a tissue. (05 Mar 2000) |