| DNA technology, recombinant | A series of procedures used to join together (recombine) DNA segments. A recombinant DNA molecule is constructed (recombined) from segments from 2 or more different DNA molecules. Under certain conditions, a recombinant DNA molecule can enter a cell and replicate there, autonomously (on its own) or after it has become integrated into a chromosome. (12 Dec 1998) |
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| technology, recombinant DNA | A series of procedures used to join together (recombine) DNA segments. A recombinant DNA molecule is constructed (recombined) from segments from 2 or more different DNA molecules. Under certain conditions, a recombinant DNA molecule can enter a cell and replicate there, autonomously (on its own) or after it has become integrated into a chromosome. (12 Dec 1998) |
| erythropoietin, recombinant | Erythropoietin prepared by recombinant DNA technology. (12 Dec 1998) |
| brucella strain 19 vaccine | A live bacterial vaccine prepared from an attenuated variant strain of Brucella abortus (strain 19); used for vaccinating cattle against brucellosis. (05 Mar 2000) |
| carrier strain | A bacterial strain that is contaminated with a bacteriophage of low infectivity. Synonym: pseudolysogenic strain. (05 Mar 2000) |
| cell strain | <cell culture> Cells adapted to culture, but with finite division potential. See: cell line. (26 Mar 1998) |
| voice strain | The development of hoarse voice secondary to overuse. (27 Sep 1997) |
| rough strain | <microbiology> Bacterial strains that have altered outer cell wall carbohydrate chains causing colonies on agar to change their appearance from smooth to dull. In Streptococci the smooth strains are virulent whereas the rough strains are not. This is partly because the rough strains are much more readily phagocytosed. (17 Dec 1997) |
| wild strain | <virology> A viral strain found naturally, as opposed to one created in the laboratory. (09 Oct 1997) |
| wild-type strain | A strain found in nature or a standard strain. See: auxotrophic strains, prototrophic strains. (05 Mar 2000) |
| congenic strain | An inbred strain of animals produced by continued crossing of a gene of one line onto another inbred (isogenic) line. (05 Mar 2000) |
| muscle strain | An acute tearing injury to muscle. Usually associated with a small amount of bleeding (haematoma) into the injured muscle tissue. (27 Sep 1997) |
| crippled strain | <microbiology> A strain of bacteria, typically highly pathogenic, that has been genetically engineered so that it cannot survive on anything but a veryspecialised medium of nutrients, this is done so that geneticists can experiment on certain pathogens without the risk that they will escape fromthe lab. (09 Oct 1997) |
| HFR strain | A strain, or clone, in which a conjugative plasmid (such as an F'), integrated in the bacterial genome, is instrumental in the transfer (along with plasmid DNA) of integrated bacterial DNA in a sequential manner to a suitable recipient. Origin: high freguency of recombination (05 Mar 2000) |
| pseudolysogenic strain | A bacterial strain that is contaminated with a bacteriophage of low infectivity. Synonym: pseudolysogenic strain. (05 Mar 2000) |