| 영문 | hormone | 한글 | 호르몬 |
|---|---|---|---|
| 설명 | 호르몬이란 특정한 내분비선에서 생성, 저장되어 있다가, 관류하는 혈액 중으로 분비된 다음 혈액에 실려 멀리 떨어져 있는 표적세포(호르몬이 작용을 나타내는 세포)에 이르러 그곳에서 특정한 기능을 발휘하는 물질을 말한다. 내분비샘이 아니더라도 어느 세포나 세포군에서 세포외액 중으로 분비된 다음 다른 세포에 가서 세포의 기능을 변동시키는 물질의 일부도 호르몬의 범주에 포함시키고 있으며 이들을 특별히 국소호르몬이라 부른다(예-아세틸콜린, 아드레날린, 콜레시스토키닌 등). 이에 비해서 특정 내분비샘에서 혈중으로 분비되는 진정한 의미의 호르몬들을 일반호르몬이라고 부른다. 호르몬을 흔히 3종의 무리로 분류를 하는데 아드레날린이나 thyroxine과 같이 아미노산의 유도체로 된 호르몬들(amine derivative), 많은 아미노산을 재료로 만들어졌거나 당단백으로 된 단백호르몬(peptide hormone), 그리고 콜레스테롤을 재료로 만들어진 지방호르몬(steroid hormone) 등으로 구분되며 이들은 대체로 종류에 따라 작용메커니즘을 달리하고 있다. |
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| 영문 | luteinizing hormone(LH) | 한글 | 황체형성호르몬 |
|---|---|---|---|
| 설명 | 여성의 월경은 정해진 순서에 의해 일어나게 된다. 먼저 난포자극호르몬이 뇌에서 분비되어 여성의 난소를 자극하게 되면 난포가 자극받아 난포호르몬(에스트로젠)을 분비하게 되고 이것은 다시 되먹이기 메커니즘 의해 뇌에 작용을 하여 황체화호르몬이 뇌에서 분비되고 이것이 이른바 절정에 이르렀을 때, 난포에서 배란이 일어나게 된다. 이후 난포는 황체로 변하게 되며, 배란된 난자가 수정되지 아니하면, 황체는 황체호르몬(프로게스테론)을 분비한 뒤 퇴화되고 곧 이어 월경이 일어나게 된다. 이 일은 정상적인 대부분의 여성에서 28일을 주기로 일어나며, 대개 황체화호르몬 절정 이후 마지막은 14일로 일정하다고 한다. |
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| HCG, hCG | Human Chorionic Gonadotropin; 사람융모성성선자극호르몬 1. Placental Glycoprotein Hormone &nbs... |
|---|---|
| APH | alcohol-positive history; alternative pathway hemolysis; aminoglycoside phosphotransferase; antepart... |
| hPFSH, HPFSH | human pituitary follicle-stimulating hormone |
| LPH | lactase-phlorizin hydrolase; left posterior hemiblock; lipotropic pituitary hormone |
| MPHD | multiple pituitary hormone deficiencies |
| receptors, pancreatic hormone | Cell surface proteins that bind pancreatic hormones with high affinity and trigger intracellular changes which influence the behaviour of cells. These include receptors for glucagon (secreted by alpha cells), insulin (secreted by beta cells), somatostatin (secreted by delta cells), and pancreatic peptide (secreted by pp cells). Some of these hormones and receptors also support neurotransmission. (12 Dec 1998) |
|---|---|
| receptors, parathyroid hormone | Cell surface proteins that bind parathyroid hormone with high affinity and trigger intracellular changes which influence the behaviour of cells. Parathyroid hormone receptors on bone, kidney, and gastrointestinal cells mediate the hormone's role in calcium and phosphate homeostasis. (12 Dec 1998) |
| receptors, thyroid hormone | Proteins, usually found in the nucleus, that specifically bind thyroid hormones and regulate DNA transcription. These proteins, termed c-erba, are activated by hormones and cause differentiation of erythroid progenitor cells which irreversibly lose proliferative potential. Thus c-erba proteins act as growth suppressors. The c-erba proteins are encoded by at least two genes, c-erba alpha and c-erba beta. Each of these has two isoforms. Mutations in the ligand-binding domain of the beta form causes thyroid hormone resistance syndrome. (12 Dec 1998) |
| receptors, thyrotropin-releasing hormone | Cell surface receptors that bind thyrotropin releasing hormone (trh) with high affinity and trigger intracellular changes which influence the behaviour of cells. Activated trh receptors in the anterior pituitary stimulate the release of thyrotropin (thyroid stimulating hormone, tsh). Trh receptors on neurons mediate neurotransmission by trh. (12 Dec 1998) |
| anterior pituitary gonadotropin | Any gonadotropin of hypophysial origin; formerly used to designate a single hormone, because it was thought that the anterior hypophysis secreted only one gonadotropin. Synonym: pituitary gonadotropic hormone. (05 Mar 2000) |
| pharyngeal pituitary | The embryonic remnant of the oral end of Rathke's pouch that is cut off from the adenohypophysis by the developing sphenoid bone; composed chiefly of chromophobes and, under normal conditions, considered physiologically inactive. See: hypophysis. (05 Mar 2000) |
| pituitary | <anatomy, endocrinology> An endocrine gland located at the base of the brain, in the small recess of a bone - certain sections of the pituitary each secretes important hormones including growth hormone (GH) and antidiuretic hormone (ADH). (16 Dec 1997) |
| pituitary adamantinoma | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| pituitary adenoma | <radiology> Benign, slow-growing, arises from adenohypophysis (anterior lobe), 5-18% of all intracranial neoplasms plain film (unreliable): enlargement of sella and sloping of the sella floor, erosion of the anterior and posterior clinoid, erosion of the dorsum sellae, calcified in less than10%, may present as a mass in the nasopharynx functioning microadenoma, less than10 mm, 20-30% of pituitary adenomas, types: prolactinoma, corticotrophic adenoma, somatotrophic adenoma, nonfunctioning macroadenoma, more than 10 mm, 70-80% of pituitary adenomas (12 Dec 1998) |
| pituitary-adrenal system | The interactions between the anterior pituitary and adrenal glands, in which corticotropin (acth) stimulates the adrenal cortex and adrenal cortical hormones suppress the production of corticotropin by the anterior pituitary. (12 Dec 1998) |
| pituitary ameloblastoma | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| pituitary apoplexy | Sudden haemorrhage into or ischemic necrosis of a normal or adenomatous pituitary gland. (12 Dec 1998) |
| pituitary cachexia | Anterior pituitary insufficiency due to trauma, vascular lesions, or tumours; usually developing postpartum as a result of pituitary necrosis caused by ischemia during a hypotensive episode during delivery; characterised clinically by asthenia, loss of weight and body hair, arterial hypotension, and manifestations of thyroid, adrenal, and gonadal hypofunction. Synonym: hypophysial cachexia, pituitary cachexia. (05 Mar 2000) |
| pituitary diverticulum | A tubular outgrowth of ectoderm from the stomodeum of the embryo; it grows dorsad toward the infundibular process of the diencephalon, around which it forms a cup-like mass, giving rise to the pars distalis and pars juxtaneuralis of the hypophysis. Synonym: craniopharyngeal canal, hypophyseal pouch, Rathke's diverticulum, Rathke's pocket, Rathke's pouch. (05 Mar 2000) |
| pituitary dwarf | Dwarfism as result of failure of growth hormone production because of hypothalamic or pituitary abnormality. Synonym: pituitary dwarf. (05 Mar 2000) |