| random mechanism | A scheme for substrate binding and product release for a multisubstrate enzyme; for a two-substrate two-product enzyme with this mechanism, either substrate can bind first and, after the reaction has taken place, either product can be the first to dissociate from the enzyme. Brain hexokinase has a random mechanism. More complex random mechanisms exist for enzymes having more than two substrates. (05 Mar 2000) |
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| random pattern flap | A flap in which the pedicle blood supply is derived randomly from the network of vessels in the area, rather than from a single longitudinal artery as in an axial pattern flap. (05 Mar 2000) |
| random sample | A group selected randomly, solely by chance. (12 Dec 1998) |
| random sampling | A selection of elements by a formal randomizing device for purposes of inference about a population of inference from that population in such a way that the probability of each possible outcome may be precisely specified in advance; the inferences are necessarily stochastic. (05 Mar 2000) |
| random variable | A variable that may assume a set of values, each with fixed probabilities or probability densities (its distribution), in such a way that the total probability assigned to the distribution is unity; the random variable may be discrete, continuous, or mixed discrete-continuous. (05 Mar 2000) |
| random walk | <cell biology> A description of the path followed by a cell or particle when there is no bias in movement. The direction of movement at any instant is not influenced by the direction of travel in the preceding period. If changes of direction are very frequent, then the displacement will be small, unless the speed is very great and the object will appear to vibrate on the spot. Although the behaviour of moving cells in a uniform environment can be described as a random walk in the long term, this is not true in the short term because of persistence. (18 Nov 1997) |
| random waves | Wave's in the electroencephalogram which occur paroxysmally and asynchronously. (05 Mar 2000) |
| mixed discrete-continuous random variable | <statistics> A random variable that may assume some values with probabilities and others with probability densities. For example, in a 35-year-old man with familial polyposis of the colon, the distribution of time until malignant disease occurs consists of a probability that he already has cancer (which would be assigned the waiting time 0), a probability density of developing it in the future and a probability that he will die of some other cause before he develops cancer. (05 Mar 2000) |
| continuous random variable | Continuous variable that may randomly assume any value in its domain but any particular value has no probability of occurring, only a probability density. (05 Mar 2000) |
| sample, random | A group selected randomly, solely by chance. (12 Dec 1998) |
| pure random drift | That which has random components only with an average value of zero and no systematic effects. Brownian movement in a still container shows pure random drift but in the Mississippi shows a steady downstream tendency. (05 Mar 2000) |
| discrete random variable | A random variable that may assume a countable number of values, each with a probability strictly greater than zero. (05 Mar 2000) |
| ordered on-random off mechanism | A scheme for substrate binding and product release for multisubstrate enzymes; for a two-substrate two-product enzyme with this mechanism, the individuals have to bind to the enzyme in a distinct order; however, once the products are formed they may dissociate from the enzyme in either order. It has been suggested that pyruvate kinase has such a mechanism. The random on-ordered off mechanism is simply the reverse of this mechanism. (05 Mar 2000) |
| airbrasive technique | A method of grinding, cutting tooth structure, or roughening the natural tooth surface or the surface of a restoration, by means of a device utilizing a gas-impelled jet of fine Al203 particles which, after striking the tooth, are removed by an aspirator. See: microetching technique. (05 Mar 2000) |
| air-gap technique | Chest radiography performed using a space between the subject and film instead of a grid to absorb scattered radiation; usually requires a target-film distance of 10 feet. (05 Mar 2000) |