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central ossifying fibroma <tumour> A painless, slow-growing, expansile, sharply circumscribed benign fibro-osseus tumour of the jaws that is derived from cells of the periodontal ligament; presents initially as a radiolucency that becomes progressively more opaque as it matures.
See: central cementifying fibroma.
(05 Mar 2000)
peripheral ossifying fibroma A reactive focal gingival overgrowth derived histogenetically from cells of the periodontal ligament and usually developing in response to local irritants (plaque and calculus) on associated teeth; consists microscopically of a hyperplastic cellular fibrous stroma supporting deposits of bone, cementum, or dystrophic calcification.
(05 Mar 2000)
periungual fibroma Multiple smooth firm nodules formed at the nail folds, often over 10 mm in length, which appear at or after puberty in some patients with tuberous sclerosis.
Synonym: Koenen's tumour.
(05 Mar 2000)
chondromyxoid fibroma <radiology> Benign metaphyseal lesion, young adults (60% less than 30 years of age), lytic lesion with well-defined margin, diaphysis of long bone, proximal TIBIA (especially tubercle) most common, NO calcification Differential diagnosis: bubbly bone lesions
(12 Dec 1998)
concentric fibroma <tumour> A benign neoplasm, actually a leiomyoma, that occupies the entire circumference of the wall of the uterus.
(05 Mar 2000)
senile fibroma A polypoid outgrowth of both epidermis and dermal fibrovascular tissue, common terminology for any small benign cutaneous lesion.
Synonym: acrochordon, fibroepithelial polyp, fibroma molle, senile fibroma, soft wart.
(05 Mar 2000)
Shope fibroma A connective tissue tumour of cottontail rabbits caused by a poxvirus of the genus Leporipoxvirus and found by Shope to be transmissible with cellular suspensions or Berkefeld filtrates; it is related to myxomatosis and is used in Europe as a source of vaccine to protect against the myxoma virus.
Synonym: rabbit fibroma.
(05 Mar 2000)
nonossifying fibroma <tumour> A loculated osteolytic focus of cellular fibrous tissue, slightly expanding a bone, usually near the end of a long bone in older children; similar to fibrous cortical defect, although larger.
(05 Mar 2000)
nonosteogenic fibroma A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter.
See: nonossifying fibroma.
Synonym: nonosteogenic fibroma.
(05 Mar 2000)
desmoplastic fibroma <tumour> A benign fibrous tumour of bone affecting children and young adults; cortical destruction may result.
(05 Mar 2000)
irritation fibroma A slow-growing nodule on the oral mucosa, composed of fibrous tissue covered by epithelium, resulting from mechanical irritation by dentures, fillings, cheek biting, etc.
(05 Mar 2000)
odontogenic fibroma <tumour> A rare odontogenic tumour found in soft tissue or as a central bony lesion. The tumour is composed of fibrous connective tissue, odontogenic epithelium, and sometimes calcification.
(05 Mar 2000)
ovarian fibroma <radiology> Bilateral in 10%, malignant counterpart (fibrosarcoma) very rare, associated with Meigs syndrome
(12 Dec 1998)
telangiectatic fibroma <tumour> A benign neoplasm of fibrous tissue in which there are numerous, small and large, frequently dilated, vascular channels.
Synonym: angiofibroma.
(05 Mar 2000)
fibroma <oncology, tumour> A benign (non-cancerous) tumour which consists of fibrous tissues or connective tissue.
(09 Oct 1997)
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