| GPT | glutamate-pyruvate transaminase; glutamic-pyruvic transaminase |
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| HPPO | high partial pressure of oxygen; hydroxyphenyl pyruvate oxidase |
| L/P | lactate/pyruvate [ratio]; liver plasma [concentration]; lymph/plasma [ratio] |
| LPK | liver pyruvate kinase |
| LPR | lactate-pyruvate ratio |
| pyruvate oxidase | <enzyme> Registry number: EC 1.2.3.3 (12 Dec 1998) |
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| pyruvate oxidation factor | <biochemistry> 1,2 dithiolane 3 valeric acid. Regarded as a coenzyme in the oxoglutarate dehydrogenase complex of the citric acid cycle. Involved generally in oxidative decarboxylations of _ keto acids. A growth factor for some organisms. (18 Nov 1997) |
| pyruvate, orthophosphate dikinase | <enzyme> An enzyme that catalyses the reaction of ATP, pyruvate, and orthophosphate to form AMP plus phosphoenolpyruvate plus pyrophosphate. Chemical name: ATP:pyruvate, orthophosphate phosphotransferase Registry number: EC 2.7.9.1 (12 Dec 1998) |
| pyruvate-formate-lyase-deactivase | <chemical> Encoded by adhe gene product from E coli; pfla (radical form) yields pfl (non-radical form) in presence of fe++, nad and CoA and the multienzyme complex consisting of alcohol plus acetaldehyde-CoA dehydrogenase activities Synonym: pfl-deactivase, adhe multienzyme, adhe gene product (26 Jun 1999) |
Synonyms : Complex, Pyruvate Dehydrogenase, Dehydrogenase Complex, Pyruvate
Synonyms : Juvenile Pyruvate Dehydrogenase Complex Deficiency Disease, Neonatal Pyruvate Dehydrogenase Complex Deficiency Disease, PDHC Deficiency Disease, Pyruvate Dehydrogenase Complex Deficiency Disease, Juvenile, Type I Ataxia with Lactic Acidosis
Synonyms : L-Type Pyruvate Kinase, M-Type Pyruvate Kinase, M1-Type Pyruvate Kinase, M2-Type Pyruvate Kinase, Pyruvate Kinase L, R-Type Pyruvate Kinase, L Type Pyruvate Kinase, M Type Pyruvate Kinase, M1 Type Pyruvate Kinase, M2 Type Pyruvate Kinase, Pyruvate Kinase, L-Type
Synonyms :
Synonyms : Oxidase, Pyruvate
| pyruvate dehydrogenase c. |
a multienzyme complex consisting of at least three distinct enzymes: pyruvate dehydrogenase (lipoamide) [EC 1.2.4.1], dihydrolipoamide S-acetyltransferase [EC 2.3.1.12], and dihydrolipoamide dehydrogenase [EC 1.8.1.4]. The integrated enzyme complex requires the cofactors thiamine pyrophosphate, lipoic acid, coenzyme A, FAD, and NAD+. It catalyzes the formation of acetyl coenzyme A from pyruvate and coenzyme A, using NAD+ as an electron acceptor; the acetyl coenzyme A is used in fatty acid synthesis, for acetylations, and for oxidation via the tricarboxylic acid cycle. Deficiency of any component of the complex results in lacticacidemia, ataxia, and psychomotor retardation. See also lipoamide dehydrogenase deficiency.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| pyruvate dehydrogenase complex |
see under complex.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| pyruvate kinase |
[EC 2.7.1.40] an enzyme of the transferase class that catalyzes the transfer of high energy phosphate from phosphoenolpyruvate to ADP to yield ATP and pyruvate; it is one of two reactions generating ATP in the Embden-Meyerhof pathway (see illustration at pathway) and a key regulatory site in this pathway. The enzyme has three distinct isozymes. Deficiency of pyruvate kinase activity in erythrocytes, an autosomal recessive trait, results in hemolytic anemia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| pyruvate kinase (PK) deficiency |
deficiency of the erythrocytic isozyme of pyruvate kinase, the most common glycolytic enzyme defect in the Embden-Meyerhof pathway; deficient product (ATP) causes chronic hemolytic anemia of widely variable severity. PK deficiency is an autosomal recessive trait and has no distinguishing clinical features from the other hemolytic disorders.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| pyruvate kinase deficiency |
hereditary blood disorder characterized by a deficiency of the enzyme pyruvate kinase. physical findings associated with the disorder may include reduced levels of oxygen-carrying hemoglobulin in the blood due to premature destruction of red blood cells (hemolytic anemia); abnormally increased levels of bilirubin in the blood (hyperbilirubinemia); abnormal enlargement of the spleen (splenomegaly); and/or other abnormalities.
출처: ipp.boku.ac.at/pz/ref/glossar1.html
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