| aklanonic acid methyl ester cyclase | <enzyme> Catalyses the formation of aklaviketone from aklanonic acid methyl ester; involved in daunomycin biosynthesis; see also daunorubicin-doxorubicin polyketide synthase Registry number: EC 5.- Synonym: aame cyclase, daud protein, daud gene product, dnrd protein, dnrd gene product (26 Jun 1999) |
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| magnesium protoporphyrin monomethyl ester oxidative cyclase | <enzyme> In chlorophyll biosynthesis converts -(ch2)2-coo-ch3 side chain of mg protoporphyrin monomethyl ester to -c=o-ch-cooch3 ring of mg 2,4-divinyl phaeoporphyrin a(5) monomethyl ester; requires NADPH and molecular oxygen; similar to cytochrome p-450 catalyzed systems but not inhibited by co Registry number: EC 1.14.13.- Synonym: mpme-oxidative cyclase (26 Jun 1999) |
| GDP-ribosyl cyclase | <enzyme> Catalyses the conversion of ngd+ (the guanine analog of nad) to cyclic GDP-ribose Registry number: EC 3.2.2.- (26 Jun 1999) |
| mannopine cyclase | <enzyme> Catalyses the conversion of mannopine to agropine Registry number: EC 5.- (26 Jun 1999) |
| geranyl pyrophosphate-sabinene hydrate cyclase | <enzyme> Enzyme from sweet marjoram; catalyses cation-dependent cyclization of geranyl pyrophosphate to cis and trans sabinene hydrate, deriving oh from water, not from the pyrophosphate ester Registry number: EC 5.5.- Synonym: sabinene hydrate cyclase, sabinene hydrate synthase (26 Jun 1999) |
| versiconal cyclase | <enzyme> From aspergillus parasiticus; catalyses the dehydration of versiconal to versicolorin b or c Registry number: EC 4.2.1.- (26 Jun 1999) |
| caryophyllene cyclase | <enzyme> Catalyses the cyclization of farnesyl pyrophosphate, probably by intramolecular electrophilic attack by c-1 bearing the pyrophosphate ester on c-11 of the terminal double bond to give a humulyl cation, which undergoes closure to a cyclobutyl intermediate and deprotonation at c-3 methyl to form (-) caryophyllene; mw 57 kD Registry number: EC 5.- (26 Jun 1999) |
| glutamine amidotransferase cyclase | <chemical> Possesses glutamine amidotransferase and cyclase activities; his7 isolated from saccharomyces cerevisiae catalyses the fifth and sixth steps of histidine biosynthesis. Synonym: his7 gene product (26 Jun 1999) |
| chanoclavin-I-cyclase | <enzyme> Converts chanoclavin I to agraclavin Registry number: EC 3.5.- (26 Jun 1999) |
| RNA 3'-terminal phosphate cyclase | <enzyme> ATP dependent; forms 2',3' terminal cyclic phosphate on RNA which is then the substrate for RNA ligase of hela cells Registry number: EC 6.5.- Synonym: RNA tph cyclase (26 Jun 1999) |
| guanylate cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanylyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| cyclase | Descriptive name applied to an enzyme that forms a cyclic compound; e.g., adenylate cyclase. (05 Mar 2000) |
| humulene cyclase | <enzyme> Catalyses the cyclization of farnesyl pyrophosphate; probably by intramolecular electrophilic attack by c-1 bearing the pyrophosphate ester on c-11 of the terminal double bond to give a humulyl cation which is stabilised by deprotonation at c-9 to form all-trans humulene; mw 57 kD Registry number: EC 5.- (26 Jun 1999) |