| prostaglandin-F synthase | <enzyme> Catalyses conversion of pgd2 to pgf2alpha; also converts pgh2 to pgf2alpha Registry number: EC 1.1.1.188 Synonym: pgd2 11-keto reductase, pgf synthetase, pgf synthase, prostaglandin d2-NADPH-dependent ketoreductase, prostaglandin f synthetase, pgf2alpha synthase, prostaglandin d2 11-keto reductase (26 Jun 1999) |
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| prostaglandins | A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes. (12 Dec 1998) |
| prostaglandins a | (13e,15s)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid (pga(1)); (5z,13e,15s)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid (pga(2)); (5z,13e,15s,17z)-15-hydroxy-9-oxoprosta-5,10,13,17-tetraen-1-oic acid (pga(3)). A group of naturally occurring secondary prostaglandins derived from pge. Pga(1) and pga(2) as well as their 19-hydroxy derivatives are found in many organs and tissues. (12 Dec 1998) |
| prostaglandins a, synthetic | Analogs or derivatives of prostaglandin a that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pga. (12 Dec 1998) |
| prostaglandins b | Physiologically active prostaglandins found in many tissues and organs. They are potent pressor substances and have many other physiological activities. (12 Dec 1998) |
| prostaglandins d | Physiologically active prostaglandins found in many tissues and organs. They show pressor activity, are mediators of inflammation, and have potential antithrombotic effects. (12 Dec 1998) |
| prostaglandins e | (11 alpha,13e,15s)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (pge(1)); (5z,11 alpha,13e,15s)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (pge(2)); and (5z,11 alpha,13e,15s,17z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (pge(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities. (12 Dec 1998) |
| prostaglandins e, synthetic | Analogs or derivatives of prostaglandins e that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pge. (12 Dec 1998) |
| prostaglandins f | (9 alpha,11 alpha,13e,15s)-9,11,15-trihydroxyprost-13-en-1-oic acid (pgf(1 alpha)); (5z,9 alpha,11,alpha,13e,15s)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (pgf(2 alpha)); (5z,9 alpha,11 alpha,13e,15s,17z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (pgf(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring pgf have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics. (12 Dec 1998) |
| prostaglandins f, synthetic | Analogs or derivatives of prostaglandins f that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pgf. (12 Dec 1998) |
| prostaglandins g | A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. most frequently encountered member of this group is the prostaglandin g2. (12 Dec 1998) |
| prostaglandins h | A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. The most frequently encountered member of this group is the prostaglandin h2. (12 Dec 1998) |
| prostaglandins, synthetic | Compounds obtained by chemical synthesis that are analogs or derivatives of naturally occurring prostaglandins and that have similar activity. (12 Dec 1998) |
Synonyms : Arachidonic Acid Cyclooxygenase, Cyclo-Oxygenase, Cyclooxygenase, Cyclooxygenases, Hydroperoxide Cyclase, PGH2 Synthetase, Prostaglandin Cyclo-Oxygenase, Prostaglandin Cyclooxygenase, Prostaglandin Endoperoxide Synthetase, Prostaglandin G-H Synthase
Synonyms : Prostanoids
Synonyms : A, Prostaglandins
Synonyms : Prostaglandin A Analogues, Synthetic Prostaglandins A, Analogs, Prostaglandin A, Analogues, Prostaglandin A, Synthetic, PGA
Synonyms : B, Prostaglandins
| prostaglandin |
a type of "tissue" hormone actively involved in many processes of human pregnancy. Tissue hormones are produced in the tissue in which they work (unlike circulating hormones produced in glands). In pregnancy, prostaglandins have a role preparing the uterus and cervix for delivery in the last days and weeks of pregnancy. Prostaglandins are also involved in headaches, arthritis, and menstrual cramping. ...
출처: www.abcbirth.com/lGlossary.html
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| prostaglandin |
Any of a class of physiologically active substances present in many tissues, with effects such as vasodilation, vasoconstriction, stimulation of intestinal or bronchial smooth muscle, uterine stimulation, and antagonism to hormones influencing lipid metabolism. Prostaglandins are prostanoic acids with side chains of varying degrees of unsaturation and varying degrees of oxidation. Often abbreviated PGA, PGB, PGC, PGD, etc. with numeric subscripts, according to structure.
출처: www.endovasc.com/glossary/glossary.html
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| prostaglandin |
Any of various oxygenated unsaturated cyclic fatty acids of animals that have a variety of hormonelike actions (as in controlling blood pressure or smooth muscle contraction). Top
출처: www.tnurology.com/uro.htm
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| prostaglandin inhibitor |
A substance that inhibits the production of prostaglandins. Nonsteroidal and steroid anti-inflammatory agents are two major categories that inhibit prostaglandins.
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| prostaglandin endoperoxide synthase |
[EC 1.14.99] an enzyme of the oxidoreductase class that has both cyclooxygenase and peroxidase activities, which together catalyze the first three reactions in the synthesis of prostaglandins and thromboxanes from arachidonic acid. Its cyclooxygenase activity catalyzes the first two reactions, each of which adds a molecule of oxygen to arachidonic acid, to form the intermediate PGG2; its peroxidase activity catalyzes the conversion of PGG2 to the intermediate PGH2, from which are formed the prostaglandins and thromboxanes. See illustration at prostaglandin.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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