| FM | face mask; facilities management; family medicine; feedback mechanism; fetal movement; fibromuscular... |
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| IDM | idiopathic disease of myocardium; immune defense mechanism; indirect method; infant of diabetic moth... |
| IRM | innate releasing mechanism; Institute of Rehabilitation Medicine |
| MoA | mechanism of action |
| POSM | patient-operated selector mechanism |
| defense mechanism | A psychological means of coping with conflict or anxiety, e.g., conversion, denial, dissociation, rationalization, repression, sublimation, the psychic structure underlying a coping strategy, immunological mechanism vs. Non-specific defense mechanism. (05 Mar 2000) |
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| double displacement mechanism | A special multisubstrate reaction in which, for a two-substrate, two-product (i.e., bi-bi) system, an enzyme reacts with one substrate to form a product and a modified enzyme, the latter then reacting with a second substrate to form a second, final product, and regenerating the original enzyme. An example of such a mechanism is found in the aminotransferases. More complex ping-pong mechanisms exist for enzymes having more than two substrates. Synonym: double displacement mechanism. (05 Mar 2000) |
| Douglas mechanism | Mechanism of spontaneous evolution in transverse lie; extreme lateral flexion of the vertebral column with birth of the lateral aspect of thorax before the buttocks. (05 Mar 2000) |
| Duncan's mechanism | Passage of the placenta from the uterus with the rough side foremost. (05 Mar 2000) |
| immunological mechanism | The groups of cells (chiefly lymphocytes and cells of the reticuloendothelial system) that function in establishing active acquired immunity (induced sensitivity, allergy). (05 Mar 2000) |
| ordered mechanism | A scheme for substrate binding and product release for multisubstrate enzymes; for a two-substrate two-product enzyme with an ordered mechanism, one particular substrate has to bind to the enzyme first followed by the other substrate; chemistry then occurs, products are formed and are released from the enzyme in a distinct order. More complex ordered schemes exist for enzymes having more than two substrates. Some of the dehydrogenases have such a mechanism. Synonym: ordered. (05 Mar 2000) |
| ordered on-random off mechanism | A scheme for substrate binding and product release for multisubstrate enzymes; for a two-substrate two-product enzyme with this mechanism, the individuals have to bind to the enzyme in a distinct order; however, once the products are formed they may dissociate from the enzyme in either order. It has been suggested that pyruvate kinase has such a mechanism. The random on-ordered off mechanism is simply the reverse of this mechanism. (05 Mar 2000) |