| SLDR | sublethal damage repair |
|---|---|
| PLA | peripheral laser angioplasty; phenyl lactate; phospholipase A; phospholipid antibody; placebo therap... |
| SLD | Sub-Lethal Damage |
| ALC | absolute lymphocyte count; acute lethal catatonia; aided living center; Alternative Lifestyle Checkl... |
| MLD | manual lymph drainage; median lethal dose; metachromatic leukodystrophy; minimal lesion disease; min... |
| dental prosthesis repair | The process of reuniting or replacing a broken or worn dental prosthesis or its part. (12 Dec 1998) |
|---|---|
| denture repair | The process of reuniting or replacing broken or worn parts of a denture. (12 Dec 1998) |
| DNA repair | <molecular biology> Each cell has a series of special enzymes to correct the errors in DNA structure and sequence. This protects genetic information against environmental damage and replication errors and restore the DNA to its original state. (25 Jun 1999) |
| DNA repair gene | A gene engaged in DNA repair. When a DNA repair gene is altered, mutations pile up throughout the DNA. (12 Dec 1998) |
| DNA repair pathway | The sequence of steps in the repair of DNA. Each step is governed by an enzyme. (12 Dec 1998) |
| error-prone repair | <molecular biology> A type of DNA repair which occurs when both nucleotides in a base pair are missing, such that it is not possible to maintain accuracy. In general, the repair proteins replace the missing nucleotides randomly. The idea is that bad DNA is better than no DNA at all. (06 Mar 1998) |
| excision repair | <molecular biology> Mechanism for the repair of environmental damage to one strand of DNA (loss of purines due to thermal fluctuations, formation of pyrimidine dimers by UV irradiation). The site of damage is recognised, excised by an endonuclease, the correct sequence is copied from the complementary strand by a polymerase and the ends of this correct sequence are joined to the rest of the strand by a ligase. The term is sometimes restricted to bacterial systems where the polymerase also acts as endonuclease. (11 Nov 1997) |
| balanced lethal system | <genetics> A population with non-linked, recessive alleles of a gene, where an individual who has two copies of the recessive allele and is therefore homozygous is dead, while an individual who has only one copy of it, and one copy of a different allele (and is heterozygous) survives. (09 Oct 1997) |
| genes, lethal | Genes which result in the premature death of the organism; dominant lethal genes kill heterozygotes, whereas recessive lethal genes kill only homozygotes. (12 Dec 1998) |
| genetic lethal | A disorder that prevents effective reproduction by those affected; e.g., Klinefelter syndrome. (05 Mar 2000) |
| granuloma, lethal midline | A non-neoplastic disease of unknown aetiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures. (12 Dec 1998) |
| chicken embryo lethal orphan virus | <virology> A virus with characteristics of adenovirus, and similar to quail bronchitis virus. Synonym: chicken embryo lethal orphan virus. (05 Mar 2000) |
| minimal lethal dose | <pharmacology> The minimal dose of a toxic substance or infectious agent that is lethal, as assayed in various experimental animals (e.g., the least amount of diphtheria toxin that, on an average, kills a 250-g guinea pig within 96 hours after subcutaneous inoculation). When followed by a subscript (generally "MLD50"), denotes the minimal dose that is lethal to a certain percentage (e.g., 50%) of animals so assayed, LD05. See: lethal dose. (05 Mar 2000) |
| clinical lethal | A disorder that culminates in premature death. (05 Mar 2000) |
| conditional-lethal mutant | A viral mutant that can replicate under some (permissive) conditions but not under other (restrictive or nonpermissive) conditions, the parent (wild type) strain being able to replicate under both conditions. See: suppressor-sensitive mutant, temperature-sensitive mutant. Synonym: conditional-lethal mutant. (05 Mar 2000) |