| 영문 | chronic active hepatitis | 한글 | 만성활동간염 |
|---|---|---|---|
| 설명 | B형 간염이나 비A형－비B형 간염의 속발증으로 나타나는 간의 만성염증이다. 같은 형태의 병이 선천성 또는 후천감마글로불린결핍증이나 어떤 종류의 약물 투여에 수반해서 나타날 수도 있다. 특징적으로 문맥부에 형질세포와 큰포식세포의 침윤, 조각괴사(간소엽 주변부 간세포의 파괴) 및 섬유증 등의 조직소견을 나타낸다. 병의 경과는 매우 다양하며 장기간의 무증상기를 보일 수도 있고 그 사이 사이에 황달, 전신쇠약, 식욕부진 및 발열 등의 증상이 나타나는 수가 있으며, 또 무월경증, 관절염, 피부발진, 혈관염, 갑상샘염, 콩팥사구체염, 궤양성대장염, 쉐그렌증후군 등 간 이외의 증상이 나타나는 수도 있고, 간경화증과 간기능상실로 진행되는 수도 있다. 자가면역메커니즘이 관여되는 것으로 추측되고 있다. |
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| 영문 | fulminant hepatitis | 한글 | 전격간염 |
|---|---|---|---|
| 설명 | 바이러스 간염의 한 형으로 급성 황색위축증이라고도 부른다. 간세포의 대부분이 괴사상태로 되며 환자는 보통 사망한다. 황달이 나타나기 전부터 이미 증상은 현저히 진행하여 황달의 출현도 빠르고, 급성 발열을 수반하며 점막이나 피하출혈을 볼 수 있다. 간의 압통을 수반하는 수도 있다. 위축에 의하여 간은 자주 작아진다. 최후에는 의식장애를 초래하여 졸음이 오고 혼미상태로 되며 간성혼수로 진행하여 사망하게 된다. 증상이 시작되어 2~3주 내에 간뇌병증까지 진행하는 간기능 상실을 전격성 간기능상실이라고 부르며, 진행 속도가 빠르지 않아서 3개월에 이르러 간기능상실에 빠지는 것은 아급성 간기능상실이라고 부른다. 모든 간염 바이러스가 모두 일으키지는 않는다. 간염A바이러스와 간염E바이러스는 보유자 상태나 만성 간염을 거의 일으키지 않는다. 기타 다른 감염 또는 비감염성 원인, 특히 약물과 독소도 본질적으로 동일한 증후를 일으킬 수 있다. 그러므로 바이러스성 간염의 진단과 각 간염 바이러스를 구별하는데는 혈청학적 검사가 필수적이다. |
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| post-term infant | A baby born 2 weeks (14 days) or more after the usual 9 months (280 days) of gestation, as calculated from the last menstrual period (lmp). This is an important calculation, since, if delivery is delayed 3 weeks beyond term, the infant mortality rate skyrockets to 3 times normal. (12 Dec 1998) |
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| post-tragus | <anatomy> A ridge within and behind the tragus in the ear of some animals. Origin: NL. See Post-, and Tragus. Source: Websters Dictionary (01 Mar 1998) |
| post-transcriptional processing | The enzymatic processing of the primary RNA transcript, which producesmessenger RNA and transfer RNA. (09 Oct 1997) |
| post-translational modification | The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation. (10 Oct 1997) |
| post-tympanic | <anatomy> Situated behind the tympanum, or in the skull, behind the auditory meatus. Origin: Pref. Post- + tympanic. Source: Websters Dictionary (01 Mar 1998) |
| heart rupture, post-infarction | Rupture of the heart after myocardial infarction. (12 Dec 1998) |
| protein processing, post-translational | Any of various enzymically catalyzed post-translational modifications of peptides or proteins in the cell of origin. These modifications include carboxylation, hydroxylation, acetylation, phosphorylation, methylation, glycosylation, oxidation-reduction, degradation and lysis, peptide bond formation, and changes in molecular weight and electrophoretic motility. (12 Dec 1998) |
| arterial transfusion | Direct transfusion from an artery of the donor into an artery of the receptor. (05 Mar 2000) |
| blood component transfusion | The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in plasmapheresis and types of cytapheresis (plateletpheresis and leukapheresis) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor. (12 Dec 1998) |
| blood transfusion | The process of infusing blood products into a patient to raise the individuals concentration of red blood cells. Blood is typed (A, B, O or AB) and crossmatched (mixed together to see if its compatible) prior to transfusion. (27 Sep 1997) |
| blood transfusion, autologous | Reinfusion of blood or blood products derived from the patient's own circulation. (12 Dec 1998) |
| blood transfusion, intrauterine | Transfusion of rh-negative blood into the peritoneal cavity of an unborn infant in the treatment of foetal erythroblastosis (erythroblastosis, foetal) in utero. (12 Dec 1998) |
| blood transfusion reaction | This refers to an immune response against transfused blood cells. Antigens, on the surface of red blood cells, are recognised as foreign proteins and can stimulate sensitised lymphocytes to produce antibodies to the red blood cell antigens. This triggers a complex immunological reaction that results in the destruction of the transfused red blood cell. The blood groups (A, B, AB, O) are classified on the basis of the presence of surface antigens on the red blood cell. Type A blood has A antigens. The plasma component of the blood contains the antibodies against all other blood group antigens other that its own. Another type of surface antigen is known as Rh factor. Rh factor is either present (Rh positive) or absent (Rh negative). Rh compatibility is another requirement for blood transfusion. Symptoms and findings of a transfusion reaction include flank pain, fever, chills, bloody urine, rash, low blood pressure, dizziness and fainting. (27 Sep 1997) |
| reciprocal transfusion | An attempt to confer immunity by transfusing blood taken from a donor into a receiver suffering from the same affection, the balance being maintained by transfusing an equal amount from the receiver to the donor. (05 Mar 2000) |
| mediate transfusion | Transfusion into a patient of blood previously obtained from a donor and stored in a suitable container. Synonym: mediate transfusion. (05 Mar 2000) |