| poliomyelitis, bulbar | A serious form of poliomyelitis in which the medulla oblongata is affected, and in which there may be dysfunction of the swallowing mechanism, and respiratory and circulatory distress. (12 Dec 1998) |
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| poliomyelitis immunoglobulin | poliomyelitis immune globulin (human) |
| poliomyelitis vaccines | Inactivated poliovirus vaccine (IPV), an aqueous suspension of inactivated strains of poliomyelitis virus (types 1, 2, and 3) used by injection; has largely been replaced by the oral vaccine. See: Salk vaccine. (05 Mar 2000) |
| poliomyelitis virus | The picornavirus (genus Enterovirus) causing poliomyelitis in humans; the route of infection is the alimentary tract, but the virus may enter the bloodstream and nervous system, sometimes causing paralysis of the limbs and, rarely, encephalitis; many infections are inapparent; serologic types 1, 2, and 3 are recognised, type 1 being responsible for most paralytic poliomyelitis and most epidemics. Synonym: poliovirus hominis, poliovirus. (05 Mar 2000) |
| accelerator globulin | Globulin in serum that promotes the conversion of prothrombin to thrombin in the presence of thromboplastin and ionised calcium. See: factor Va, factor V, serum accelerator globulin. (05 Mar 2000) |
| albumin-globulin ratio | The ratio of albumin to globulin in the serum or in the urine in kidney disease; the normal ratio in the serum is approximately 1.55. (05 Mar 2000) |
| alpha-globulin | <protein> The serum globulins with the most rapid electrophoretic migration, further subdivided into faster alpha(1)- and slower alpha(2)-globulins. (12 Dec 1998) |
| antihemophilic globulin | A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs. (12 Dec 1998) |
| antihemophilic globulin A | A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs. (12 Dec 1998) |
| antihemophilic globulin B | <chemical> Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, ixa, forms a complex with factor viii and calcium on platelet factor 3 to activate factor x to xa. Deficiency of factor ix results in christmas disease (haemophilia b). Chemical name: Blood-coagulation factor IX (12 Dec 1998) |
| antihuman globulin | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| antilymphocyte globulin | <protein> Antibodies which attach to and destroy lymphocytes. This may be used clinically by injection into a vein, for example in aplastic anaemia. (13 Nov 1997) |
| b1C globulin | The third component (C3) of complement. See: component of complement. (05 Mar 2000) |
| b1E globulin | The fourth component (C4) of complement. See: component of complement. (05 Mar 2000) |
| b1F globulin | The fifth component (C5) of complement. See: component of complement. (05 Mar 2000) |
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