| SMART | Somatic Mutation And Recombination Test |
|---|---|
| MCR | mutation cluster region |
| M(f) | mutation frequency |
| Tfm | testicular feminization mutation |
| polar presentation | The presentation of either pole of the foetal oval; may be either a cephalic or breech presentation, or a longitudinal lie. (05 Mar 2000) |
|---|---|
| polar ring | A thickened, electron-dense ring at the anterior end of certain stages of the Apicomplexa; part of the apical complex characteristic of these sporozoans. (05 Mar 2000) |
| polar solvents | Solvent's that exhibit polar forces on solutes, due to high dipole moment, wide separation of charges, or tight association; e.g., water, alcohols, acids. (05 Mar 2000) |
| polar star | One of the figures forming the diaster. Synonym: polar star. (05 Mar 2000) |
| polar zone | The region in the vicinity of an electrode applied to the body. See: electrotonus. (05 Mar 2000) |
| electro-polar | <physics> Possessing electrical polarity; positively electrified at one end, or on one surface, and negatively at the other; said of a conductor. Source: Websters Dictionary (01 Mar 1998) |
| zinco-polar | <physics> Electrically polarized like the surface of the zinc presented to the acid in a battery, which has zincous affinity. Source: Websters Dictionary (01 Mar 1998) |
| law of polar excitation | A given segment of a nerve is irritated by the development of catelectrotonus and the disappearance of anelectrotonus, but the reverse does not hold; i.e., excitation occurs at the cathode when the circuit is closed and at the anode when it is opened. Synonym: Pfluger's law. (05 Mar 2000) |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| back mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| germinal mutation | A mutation in the germ cells (the cells which will undergo meiosis to form the gametes). Such mutations are therefore passed on to offspring. (09 Oct 1997) |