| 영문 | hormone | 한글 | 호르몬 |
|---|---|---|---|
| 설명 | 호르몬이란 특정한 내분비선에서 생성, 저장되어 있다가, 관류하는 혈액 중으로 분비된 다음 혈액에 실려 멀리 떨어져 있는 표적세포(호르몬이 작용을 나타내는 세포)에 이르러 그곳에서 특정한 기능을 발휘하는 물질을 말한다. 내분비샘이 아니더라도 어느 세포나 세포군에서 세포외액 중으로 분비된 다음 다른 세포에 가서 세포의 기능을 변동시키는 물질의 일부도 호르몬의 범주에 포함시키고 있으며 이들을 특별히 국소호르몬이라 부른다(예-아세틸콜린, 아드레날린, 콜레시스토키닌 등). 이에 비해서 특정 내분비샘에서 혈중으로 분비되는 진정한 의미의 호르몬들을 일반호르몬이라고 부른다. 호르몬을 흔히 3종의 무리로 분류를 하는데 아드레날린이나 thyroxine과 같이 아미노산의 유도체로 된 호르몬들(amine derivative), 많은 아미노산을 재료로 만들어졌거나 당단백으로 된 단백호르몬(peptide hormone), 그리고 콜레스테롤을 재료로 만들어진 지방호르몬(steroid hormone) 등으로 구분되며 이들은 대체로 종류에 따라 작용메커니즘을 달리하고 있다. |
||
| 영문 | luteinizing hormone(LH) | 한글 | 황체형성호르몬 |
|---|---|---|---|
| 설명 | 여성의 월경은 정해진 순서에 의해 일어나게 된다. 먼저 난포자극호르몬이 뇌에서 분비되어 여성의 난소를 자극하게 되면 난포가 자극받아 난포호르몬(에스트로젠)을 분비하게 되고 이것은 다시 되먹이기 메커니즘 의해 뇌에 작용을 하여 황체화호르몬이 뇌에서 분비되고 이것이 이른바 절정에 이르렀을 때, 난포에서 배란이 일어나게 된다. 이후 난포는 황체로 변하게 되며, 배란된 난자가 수정되지 아니하면, 황체는 황체호르몬(프로게스테론)을 분비한 뒤 퇴화되고 곧 이어 월경이 일어나게 된다. 이 일은 정상적인 대부분의 여성에서 28일을 주기로 일어나며, 대개 황체화호르몬 절정 이후 마지막은 14일로 일정하다고 한다. |
||
| hPFSH, HPFSH | human pituitary follicle-stimulating hormone |
|---|---|
| LPH | lactase-phlorizin hydrolase; left posterior hemiblock; lipotropic pituitary hormone |
| MPHD | multiple pituitary hormone deficiencies |
| NPA-NIHHDP | National Pituitary Agency-National Institutes of Health Hormone Distribution Program |
| PATH | pathology, pathological; pituitary adrenotropic hormone; physicians at teaching hospitals |
| pituitary adamantinoma | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
|---|---|
| pituitary adenoma | <radiology> Benign, slow-growing, arises from adenohypophysis (anterior lobe), 5-18% of all intracranial neoplasms plain film (unreliable): enlargement of sella and sloping of the sella floor, erosion of the anterior and posterior clinoid, erosion of the dorsum sellae, calcified in less than10%, may present as a mass in the nasopharynx functioning microadenoma, less than10 mm, 20-30% of pituitary adenomas, types: prolactinoma, corticotrophic adenoma, somatotrophic adenoma, nonfunctioning macroadenoma, more than 10 mm, 70-80% of pituitary adenomas (12 Dec 1998) |
| pituitary-adrenal system | The interactions between the anterior pituitary and adrenal glands, in which corticotropin (acth) stimulates the adrenal cortex and adrenal cortical hormones suppress the production of corticotropin by the anterior pituitary. (12 Dec 1998) |
| pituitary ameloblastoma | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| pituitary apoplexy | Sudden haemorrhage into or ischemic necrosis of a normal or adenomatous pituitary gland. (12 Dec 1998) |
| pituitary cachexia | Anterior pituitary insufficiency due to trauma, vascular lesions, or tumours; usually developing postpartum as a result of pituitary necrosis caused by ischemia during a hypotensive episode during delivery; characterised clinically by asthenia, loss of weight and body hair, arterial hypotension, and manifestations of thyroid, adrenal, and gonadal hypofunction. Synonym: hypophysial cachexia, pituitary cachexia. (05 Mar 2000) |
| pituitary diverticulum | A tubular outgrowth of ectoderm from the stomodeum of the embryo; it grows dorsad toward the infundibular process of the diencephalon, around which it forms a cup-like mass, giving rise to the pars distalis and pars juxtaneuralis of the hypophysis. Synonym: craniopharyngeal canal, hypophyseal pouch, Rathke's diverticulum, Rathke's pocket, Rathke's pouch. (05 Mar 2000) |
| pituitary dwarf | Dwarfism as result of failure of growth hormone production because of hypothalamic or pituitary abnormality. Synonym: pituitary dwarf. (05 Mar 2000) |
| pituitary dwarfism | Short stature due to underpreformance of the pituitary gland (specifically of the anterior pituitary). (12 Dec 1998) |
| pituitary fossa | Fossa of the sphenoid bone housing the pituitary gland. See: sella turcica. Synonym: fossa hypophysialis, pituitary fossa. (05 Mar 2000) |
| pituitary gigantism | Excessive growth due to overactivity of the pituitary gland (specifically of the anterior pituitary). (12 Dec 1998) |
| pituitary gland | A small oval shaped endocrine gland situated at the base of the brain in the fossa (depression) of the sphenoid bone. The overall role is to regulate growth and metabolism. The gland is divided into the posterior and anterior pituitary, each responsible for the production of its own unique hormones. (27 Sep 1997) |
| pituitary gland, anterior | The glandular or anterior lobe of the pituitary gland. (12 Dec 1998) |
| pituitary gland, posterior | The neural or post-neural lobe of the pituitary gland. (12 Dec 1998) |
| pituitary gonadotropins | gonadoprophins |