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phosphatidylinositol 4,5-diphosphate <biochemistry> A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase c, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase.
(12 Dec 1998)
phosphatidylinositol 4-phosphate <biochemistry> The intermediate in the biosynthesis of phosphatidylinositol 4,5-bisphosphate from phosphatidylinositol.
(20 Sep 2002)
phosphatidylinositol 4-phosphate phosphatase <enzyme> From human erythrocyte membranes
Registry number: EC 3.1.3.-
Synonym: ptdins-4p-phosphatase, phosphatidylinositol-4-phosphate monoesterase, ptdins4p monoesterase
(26 Jun 1999)
phosphatidylinositol-ceramide phosphoinositol transferase <enzyme> Involved in biosynthesis of inositol-containing sphingolipids; isolated from saccharomyces cerevisiae
Registry number: EC 2.4.1.-
Synonym: ipc synthase
(26 Jun 1999)
phosphatidylinositol synthase <enzyme> An enzyme that catalyses the reaction of CDP-diacylglycerol with inositol to form CMP and phosphatidylinositol; found in the endoplasmic reticulum.
(20 Sep 2002)
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase <enzyme> Involved in formation of glycosylphosphatidyl inositol membrane anchors in trypanosoma brucei; forms glucosaminyl-phosphatidylinositol
Registry number: EC 3.5.1.-
Synonym: glcnac-pi de-n-acetylase, pig-l protein, phosphatidylinositol glycan class l protein, n-acetylglucosaminyl-phosphatidylinositol deacetylase
(26 Jun 1999)
1-phosphatidylinositol 3-kinase <enzyme> An enzyme that catalyses the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, v(d)j recombination and cell cyle checkpoints.37.
Chemical name: ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
Registry number: EC 2.7.1.137
(12 Dec 1998)
1-phosphatidylinositol 4-kinase <enzyme> An enzyme that catalyses the conversion of phosphatidylinositol to phosphatidylinositol 4-phosphate, the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.
Chemical name: ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate
Registry number: EC 2.7.1.67
(12 Dec 1998)
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