| PE | Edinburgh Pharmacopoeia; pancreatic extract; paper electrophoresis; partial epilepsy; pelvic examina... |
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| PS | pacemaker syndrome; paired stimulation; paradoxical sleep; paraspinal; parasympathetic; Parkinson sy... |
| phosphatidylinositol | <biochemistry> A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide. It is a very important minor phospholipid in eukaryotes, involved in signal transduction processes. Contains myo inositol linked through the 1 hydroxyl group to phosphatidic acid. The 4 phosphate (PIP) and 4, 5 bisphosphate derivatives PIP2) are formed and broken down in membranes by the action of specific kinases and phosphatases (futile cycles). Signal sensitive phospholipase C enzymes remove the inositol moiety, in particular from 1,4,5 trisphosphate (PIP2) as inositol 1,4,5 triphosphate (Ins P3: IP3). Both the diacyl glycerol and products act as second messengers. Synonym: phosphoinositide. (20 Sep 2002) |
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| phosphatidylinositol 4,5-bisphosphate | <biochemistry> This is a molecule of phosphatidylinositol with two additional sites of phosphorylation. It is an important constituent of cell membrane phospholipids as well as a precursor of the second messengers, diacylglycerol and inositol 1,4,5-trisphosphate. Acronym: PIP2 (20 Sep 2002) |
| phosphatidylinositol 4,5-bisphosphate kinase | <enzyme> Membrane-associated enzyme Registry number: EC 2.7.1.- Synonym: ptdins 4,5-p2 kinase, phosphatidylinositol 4,5-bisphosphate kinase, ptdins(4,5)p2 3oh-kinase (26 Jun 1999) |
| phosphatidylinositol 4,5-diphosphate | <biochemistry> A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase c, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (12 Dec 1998) |
| phosphatidylinositol 4-phosphate | <biochemistry> The intermediate in the biosynthesis of phosphatidylinositol 4,5-bisphosphate from phosphatidylinositol. (20 Sep 2002) |
| phosphatidylinositol 4-phosphate phosphatase | <enzyme> From human erythrocyte membranes Registry number: EC 3.1.3.- Synonym: ptdins-4p-phosphatase, phosphatidylinositol-4-phosphate monoesterase, ptdins4p monoesterase (26 Jun 1999) |
| phosphatidylinositol phosphates | <biochemistry> Phosphatidylinositols in which one or more alcohol group of the inositol has been substituted with a phosphate group. (12 Dec 1998) |
| phosphatidylinositol synthase | <enzyme> An enzyme that catalyses the reaction of CDP-diacylglycerol with inositol to form CMP and phosphatidylinositol; found in the endoplasmic reticulum. (20 Sep 2002) |
| phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase | <enzyme> Hydrolyzes the 5-position phosphate of ptdins(3,4,5)p3 forming phosphatidylinositol-3,4-bisphosphate; an isoenzyme forms a complex with the p85/p110 form of pi 3-kinase Registry number: EC 3.1.3.- Synonym: ptdins(3,4,5)p3 5-phosphatase, pi(3,4,5)p3 5-pase (26 Jun 1999) |
| phosphatidylinositol-3-phosphatase | <enzyme> Hydrolyzes phosphatidylinositol 3-phosphate in nih 3t3 cells; specific as it has little or no activity on the monoester phosphates of ptdins(4)p, ptdins(4,5)p2, or inositol 1,3-bisphosphate; does not require added metal ions for activity and is maximally active in the presence of edta; inhibited by ca(2+), mg(2+),zn(2+), and the phosphatase inhibitor vo(3-)4 Registry number: EC 3.1.3.64 Synonym: phosphatidylinositol 3-phosphatase (26 Jun 1999) |
| phosphatidylinositol-ceramide phosphoinositol transferase | <enzyme> Involved in biosynthesis of inositol-containing sphingolipids; isolated from saccharomyces cerevisiae Registry number: EC 2.4.1.- Synonym: ipc synthase (26 Jun 1999) |
| phosphatidylinositols | <biochemistry> Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myo-inositol. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid, myo-inositol, and 2 moles of fatty acids. (12 Dec 1998) |
| phosphatidylserine | <biochemistry> The condensation product of phosphatidic acid and serine, found in biomembranes. It is an important minor species of phospholipid in membranes. Serine is attached to phosphatidic acid by a phosphodiester linkage. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and serine and 2 moles of fatty acids. Synthesis is from phosphatidylethanolamine by exchange of ethanolamine for serine. Distribution is asymmetric, as the molecule is only present on the cytoplasmic side of cellular membranes. It is negatively charged at physiological pH and interacts with divalent cations, involved in calcium dependent interactions of proteins with membranes (e.g. Protein kinase C). See: cephalin. (20 Sep 2002) |
Synonyms : Ethanolamineglycerophospholipids, Phosphoglycerides, Ethanolamine
Synonyms : Phosphatidyl Glycerol, Glycerol, Phosphatidyl, Phosphoglycerides, Glycerol
Synonyms : Phosphatidylinositol 4, 5-Biphosphate, PtIns 4, 5-P2, 4, 5-Biphosphate, Phosphatidylinositol, 4, 5-Diphosphate, Phosphatidylinositol, Phosphatidylinositol 4, 5 Biphosphate, Phosphatidylinositol 4, 5 Bisphosphate, Phosphatidylinositol 4, 5 Diphosphate
Synonyms : GPI-PLC, Glycosylphosphatidylinositol-Specific Phospholipase C, Monophosphatidylinositol Phosphodiesterase, Phosphatidylinositol-Glycan-Specific Phospholipase C, Phosphatidylinositol-Specific Phospholipase C, Phosphoinositide Phosphodiesterase C
Synonyms : Phosphatidyl Inositol Phosphates, Polyphosphoinositide, Inositol Phosphates, Phosphatidyl, Phosphates, Phosphatidyl Inositol, Phosphates, Phosphatidylinositol
| phosphatidylcholine–sterol O |
[EC 2.3.1.43] an enzyme of the transferase class, secreted by the liver, that catalyzes the formation of cholesteryl esters in high-density lipoproteins by transferring long-chain fatty acid residues from phosphatidylcholine to a sterol. The reaction is a step in the synthesis of lipoproteins. Deficiency of the enzyme, an autosomal recessive trait, is called lecithin–cholesterol acyltransferase (LCAT) deficiency. Called also lecithin–cholesterol acyltransferase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| phosphatidylethanolamine |
a phospholipid in which ethanolamine is attached to the phosphate group of phosphatidic acid by an ester linkage; it is a major constituent of cell membranes and is localized preferentially in the inner surface of the plasma membrane.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| phosphatidylinositol |
a phospholipid in which the sugar inositol is attached to the phosphate group of phosphatidic acid by an ester linkage and the fatty acyl groups are usually arachidonate and stearate; additional phosphates can be attached to the sugar. It is a minor constituent of cell membranes found primarily in the plasma membrane. It is converted by specific kinases to mono- and diphosphorylated forms, phosphoinositides involved in hormonally activated calcium mobilization.
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| phosphatidylinositol deacylase |
[EC 3.1.1.52] formal EC nomenclature for a phospholipase A2 specific for phosphatidylinositol. See phospholipase A2.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| phosphatidylserine |
Numerous double-blind studies have shown that PS consistently benefits memory, learning, concentration, word choice, and mood. PS raises brain energy, integrates electrical activity across the brain zones, improves mood, restores hormones that are out of rhythm, and improves coordination between the brain and its adrenal organs which helps us cope with stress.
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