| AAG | 3-alkaladenine deoxyribonucleic acid glycosylase; allergic angiitis and granulomatosis; alpha-1-acid... |
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| CGGE | constant gradient gel electrophoresis |
| DGGE | denaturating gradient gel electrophoresis |
| ECPOG | electrochemical potential gradient |
| GE | gastric empyting; gastroemotional; gastroenteritis; gastroenterology; gastroenterostomy; gastroesoph... |
| critical gradient | <botany> The maximum stable inclination of an unsupported slope under the most adverse conditions that it will likely experience, as determined by current engineering technology. (09 Oct 1997) |
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| pseudospatial gradient sensing | <cell biology> Mechanism for sensing a gradient of a diffusible chemical in which the cell sends protrusions out at random, up gradient protrusions are stabilised by positive feedback (because receptor occupancy is rising with time) and others are transitory because of adaptation. Possibly the mechanism by which neutrophils sense chemotactic gradients. (18 Nov 1997) |
| density gradient | <chemistry> A column of liquid in which the density varies continually with position, usually as a consequence of variation of concentration of a solute. Such gradients may be established by progressive mixing of solutions of different density as for example: sucrose gradients) or by centrifuge induced redistribution of solute (as for caesium chloride gradients). Density gradients are widely used for centrifugal and gravity induced separations of cells, organelles and macromolecules. The separations may exploit density differences between particles or primarily differences in size, in which latter case the function of the gradient is chiefly to stabilise the liquid column against mixing. (12 Jan 1998) |
| density gradient centrifugation | <technique> High-speed centrifugation inwhich molecules float at a point wheretheir density equals that in a gradient of cesium chloride or sucrose. (12 Jan 1998) |
| systolic gradient | The difference in pressure during systole between two communicating cardiovascular chambers, e.g., between the left ventricle and aorta in aortic stenosis. (05 Mar 2000) |
| electrochemical gradient | A measure of the tendency of an ion to move passively from one point to another, taking into consideration the differences in its concentration and in the electrical potentials between the two points; commonly expressed as the additional voltage needed to achieve equilibrium. (05 Mar 2000) |
| ficoll gradient | A density gradient of ficoll (synthetic sucrose polymer) in solution, where concentration of the ficoll varies continuously through the solution. It is often used to separate different types of cells from each other during the process of sedimentation. (09 Oct 1997) |
| field gradient | In magnetic resonance imaging, a magnetic field that varies with location, superimposed on the uniform field of the magnet, to alter the resonant frequency of nuclei and allow recovery of their spatial position. Synonym: field gradient. (05 Mar 2000) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| acceleration phase | <cell biology, cell culture> A period of increasing growth before the log phase in a culture of microbes. After the culture is started on a medium, at first there is no growth (the lag phase) and then the microbes start to gradually grow (acceleration phase) until they reach a constant maximum rate of growth (log phase). (15 Jan 1998) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acute-phase reaction | <immunology, rheumatology> Refers to the changes in synthesis of certain proteins within the serum during an inflammatory response, which provides rapid protection for the host against microorganisms via non-specific defense mechanisms. It consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma; the reaction is mediated by endogenous pyrogens, the hypothalamus, adrenal hormones, and other factors. (12 Jul 2000) |
| anal phase | In psychoanalytic personality theory, the stage of psychosexual development, occurring when a child is between 1 and 3 years, during which activities, interests, and concerns are centreed around the anal zone. (05 Mar 2000) |
| aqueous phase | The water portion of a system consisting of two liquid phase's, one mainly water, the other a liquid immiscible with water (e.g., benzene, ether). (05 Mar 2000) |
| blast phase | Refers to advanced chronic myelogenous leukaemia. In this phase, the number of immature, abnormal white blood cells in the bone marrow and blood is extremely high. Also called blast crisis. (12 Dec 1998) |