| RCT | radiotherapy and chemotherapy; randomized clinical trial; randomized controlled trial; registered ca... |
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| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
| CS | calf serum; campomelic syndrome; carcinoid syndrome; cardiogenic shock; caries-susceptible; carotid ... |
| ILP | inadequate luteal phase; insufficiency of luteal phase; interstitial laser photocoagulation; interst... |
| SPIA | solid-phase immunoabsorption; solid-phase immunoassay |
| randomised controlled trial | A clinical trial that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table. Treatment allocations using coin flips, odd-even numbers, patient social security numbers, days of the week, medical record numbers, or other such pseudo- or quasi-random processes, are not truly randomised and a trial employing any of these techniques for patient assignment is designated simply a controlled clinical trial. (12 Dec 1998) |
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| randomised trial | <statistics> A clinical trial in which patients have been randomly assigned to receive either the study drug or alternative treatment, in which neither the patient nor the physician conducting the study know which treatment is being given the patient, and in which the alternative to the study drug is a placebo, the study is conducted at several centres. (09 Oct 1997) |
| controlled trial | A clinical study in which one group of participants receives an experimental drug while another group receives either a placebo or an approved standard therapy. When participants do not know which group they are in, the trial is blinded. See: Double-Blind. (09 Oct 1997) |
| open-label trial | A study in which both researchers and participants know what drug a person is taking and at what dose. (09 Oct 1997) |
| trial | 1. The act of trying or testing in any manner. Specifically: Any effort or exertion of strength for the purpose of ascertaining what can be done or effected. "[I] defy thee to the trial of mortal fight." (Milton) The act of testing by experience; proof; test. "Repeated trials of the issues and events of actions." (Bp. Wilkins) Examination by a test; experiment, as in chemistry, metallurgy, etc. 2. The state of being tried or tempted; exposure to suffering that tests strength, patience, faith, or the like; affliction or temptation that exercises and proves the graces or virtues of men. "Others had trial of cruel mockings and scourgings." (Heb. Xi. 36) 3. That which tries or afflicts; that which harasses; that which tries the character or principles; that which tempts to evil; as, his child's conduct was a sore trial. "Every station is exposed to some trials." (Rogers) 4. The formal examination of the matter in issue in a cause before a competent tribunal; the mode of determining a question of fact in a court of law; the examination, in legal form, of the facts in issue in a cause pending before a competent tribunal, for the purpose of determining such issue. Synonym: Test, attempt, endeavor, effort, experiment, proof, essay. See Test, and Attempt. Origin: From Try. Source: Websters Dictionary (01 Mar 1998) |
| trial and error | The apparently random, haphazard, hit-or-miss exploratory activity which often precedes the acquisition of new information or adjustments; it may be overt, as in a rat running in a maze, or covert (vicarious), as when one thinks of various ways of coping with a situation. (05 Mar 2000) |
| trial base | <cell biology> A hypothetical cell adhesion molecule possibly involved in sponge cell adhesion, existence unproven. (18 Nov 1997) |
| trial case | In refraction, a box containing lenses for testing. (05 Mar 2000) |
| trial denture | A setup of artificial teeth so fabricated that it may be placed in the patient's mouth to verify esthetics, for the making of records, or for any other operation deemed necessary before final completion of the denture. Synonym: wax model denture. (05 Mar 2000) |
| trial frame | A type of spectacle frame with variable adjustments, for holding trial lenses during refraction. (05 Mar 2000) |
| trial lenses | A series of cylindrical and spherical lens's used in testing vision. (05 Mar 2000) |
| trial of labour | Allowing a woman to be in labour long enough to determine if vaginal birth may be anticipated. (12 Dec 1998) |
| angiotensin III | <chemical> A heptapeptide formed by the enzymatic hydrolysis of angiotensin II. It has greater activity than angiotensin II for stimulating aldosterone synthesis and in the release of prostaglandins but only 20% of the pressor activity. Chemical name: Angiotensin II, 1-de-L-aspartic acid- (12 Dec 1998) |
| annexin III | <enzyme> A protein of the annexin family that catalyses the conversion of 1-d-inositol 1,2-cyclic phosphate and water to 1-d-myo-inositol 1-phosphate. Chemical name: 1-D-myo-Inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase Registry number: EC 3.1.4.36 (12 Dec 1998) |
| antithrombin III | <haematology> Antithrombin III is a protein which stimulates the removal of blood clots in the bloodstream. Small blood clots form normally within the bloodstream, but are normally dissolved via the bodys antithrombin III. Conditions that may have an associated low value of antithrombin III include: liver disease and DIC. Normal values are: 0.20 to 0.45 mg/ml or more than 50% of the laboratory control value. Conditions where there is a deficiency of this important protease inhibitor can result in a condition of hypercoagulation, resulting in an increased risk for blood clot formation. Inheritance: autosomal dominant. (13 Jan 1998) |