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phase I trial Includes initial introduction of an investigational new drug into humans. These studies typically involve seriously ill patients for whom no effective standard therapies are available. Phase I trials are designed to determine the metabolic and pharmacological actions of the drug in humans, the side effects associated with increasing doses (to establish a safe dose range), and, if possible, to gain early evidence of effectiveness; they are typically closely monitored. ...
Ãâó: www.umich.edu/~newsinfo/Releases/2001/Aug01/glossa...
phase I trial Clinical research protocol to establish the toxicity of a new treatment. Phase II Trial: Clinical research protocol to establish the value of a new treatment. Phase III Trial: Clinical research protocol to improve present standard therapy. Top of page
Ãâó: www.rationaltherapeutics.com/reference/glossary.ht...
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