| MAP | malignant atrophic papulosis; mandibular angle plane; maturation-activated protein; maximal aerobic ... |
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| MDFD | map-dot-fingerprint dystrophy |
| macrorestriction map | <molecular biology> Map depicting the order of and distance between sites at which restriction enzymes cleave chromosomes. (09 Oct 1997) |
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| map | 1. A representation of the surface of the earth, or of some portion of it, showing the relative position of the parts represented; usually on a flat surface. Also, such a representation of the celestial sphere, or of some part of it. There are five principal kinds of projection used in making maps: the orthographic, the stereographic, the globuar, the conical, and the cylindrical, or Mercator's projection. See Projection. 2. Anything which represents graphically a succession of events, states, or acts; as, an historical map. "Thus is his cheek the map of days outworn. <botany>" (Shak) Map lichen, a lichen (Lecidea geographica) growing on stones in curious maplike figures. Origin: From F. Mappe, in mappemonde map of the world, fr. L. Mappa napkin, signal cloth; a Punic word. Cf. Apron, Napkin, Nappe. Source: Websters Dictionary (01 Mar 1998) |
| map, contig | A map depicting the relative order of a linked library of small overlapping clones representing a complete chromosome segment. (12 Dec 1998) |
| map distance | The degree of separation of two loci on a linkage map, measured in morgans or centimorgans. (05 Mar 2000) |
| map-dot-fingerprint dystrophy | Fingerprint dystrophy accompanied by map-like patterns and microcystic epithelial inclusions. (05 Mar 2000) |
| MAP kinase | Mitogen activated protein kinases. (ERKs: externally regulated kinases) Serine threonine kinases that are activated when quiescent cells are treated with mitogens and therefore potentially transmit signal for entry into cell cycle. One target is trancription factor p62TCF. MAP kinase itself can be phosphorylated by MAP kinase kinase and this may in turn be controlled by RAF 1. Confusingly, do phosphorylate microtubule-associated proteins. (18 Nov 1997) |
| MAP kinase kinase kinase | <enzyme> From pc12 cells; reactivates map kinase kinase inactivated by protein phosphatase 2a by phosphorylation of serine residues; tak1 (tgf-beta-activated kinase 1) is a member of the mapkkk family; genbank ab006787 (mouse) Registry number: EC 2.7.10.- Synonym: mapkkk, tak1 mapkkk, ask1 (kinase), apoptosis signal-regulating kinase 1 (26 Jun 1999) |
| map, linkage | A map of the genes on a chromosome based on linkage analysis. A linkage map does not show the physical distances between genes but rather their relative positions, as determined by how often two gene loci are inherited together. The closer two genes are (the more tightly they are linked), the more often they will be inherited together. Linkage distance is measured in centimorgans (cm). (12 Dec 1998) |
| map, physical | A map of the locations of identifiable landmarks on chromosomes. Physical distance is measured in base pairs. The physical map differs from the genetic map which is based purely on genetic linkage data. In the human genome, the lowest-resolution physical map is the banding patterns of the 24 different chromosomes. The highest-resolution physical map is the complete nucleotide sequence of all chromosomes, a future goal. (12 Dec 1998) |
| genetic map | <genetics> A map of the relative positions of genetic loci on a chromosome, determined onthe basis of how often the loci are inherited together. Distance ismeasured in centimorgans (cM). (09 Oct 1997) |
| restriction map | <molecular biology> Map of DNA showing the position of sites recognised and cut by various restriction endonucleases. (12 Jan 1998) |
| peptide map | Proteases will produce fragments of a characteristic size from a protein and this can be used as a test for the identity or otherwise of two similar sized proteins. It is possible to produce a peptide fragment map from a single gel band. (18 Nov 1997) |
| chromosomal map | A formal, stylised representation of the karyotype and of the positioning and ordering on it of those loci that have been localised by any of several mapping methods. (05 Mar 2000) |
| chromosome map | The chart of the linear array of genes on a chromosome. The Human Genome Project aims to map all of the human chromosomes. (12 Dec 1998) |
| physical map | <molecular biology> A map of the locations of identifiable landmarks on DNA (for example, restriction enzyme cutting site, genes), regardless of inheritance. Distance is measured in base pairs. For the human genome, the lowest-resolution physical map is the banding patterns on the 24 different chromosomes, the highest-resolution map wouldbe the complete nucleotide sequence of the chromosomes. (09 Oct 1997) |