| q beta phage | <molecular biology> A single-stranded RNA phage that specifically infects enterobacteria containing the f plasmid. It is widely used to study RNA phage and bacterial cell function. (10 Oct 1997) |
|---|---|
| tailed phage | A member of a group of hundreds of DNA-based bacteria-infecting viruses which are characterised by a helix-shaped tail and a cube-shaped head.This group includes the viral families Myoviridae, Podoviridae, andSiphoviridae. (09 Oct 1997) |
| temperate phage | A bacteriophage that integrates its DNA into that of the host (lysogeny) as opposed to virulent phages that lyse the host. (18 Nov 1997) |
| T even phage | <microbiology> A group of dsDNA bacteriophages of enterobacteria including T2, T4, T6 as opposed to T odd phage (T1, 3, 5 and 7) (18 Nov 1997) |
| lambda phage | <virology> Bacterial DNA virus, first isolated from E. Coli. Its structure is similar to that of the T even phages. Lambda genetic material consists of a double-stranded DNA molecule with 5' twelve-base-pair sticky ends, known as cos sites, which permit circularisation of the DNA molecule. It shows a lytic cycle and a lysogenic cycle and studies on the control of these alternative cycles have been very important for our understanding of the regulation of gene transcription. It is used as a cloning vector, accommodating fragments of DNA up to 15 kilobase pairs long. For larger pieces, the cosmid vector was constructed from its ends. (14 Mar 2000) |
| lytic phage | A bacteriophage (virus which infects bacteria) that can only follow the lytic pathway to completing its lytic cycle, and does not have the mechanisms to enter the lysogenic pathway. (09 Oct 1997) |
| alu-equivalent family | A set of sequences in a mammalian genome that is related to the human Alu family. (05 Mar 2000) |
| alu family | A set of dispersed sequences in the human genome having Alu cleavage sites at each end. (05 Mar 2000) |
| cancer family | A group of blood relatives of whom several have had cancer; the mode of aggregation may be genetic and homogeneous, as in familial polyposis of the colon; diverse as in neurofibromatosis; or due to common exposure to a carcinogenic or oncogenic agent, such as a virus. (05 Mar 2000) |
| gene family | <molecular biology> A set of genes coding for diverse proteins which, by virtue of their high degree of sequence similarity, are believed to have evolved from a single ancestral gene. An example is the immunoglobulin family where the characteristic features of the constant domains are found in various cell surface receptors. (18 Nov 1997) |
| physicians, family | Those physicians who have completed the education requirements specified by the american academy of family physicians. (12 Dec 1998) |
| colon cancer, family history of | Colorectal cancer can run in families. The colon cancer risk is higher if an immediate (first-degree) family member (parents, siblings or children) had colorectal cancer and even higher if more than one such relative had colorectal cancer or if a family member developed the cancer at young age (younger than 55 years). Under any of these circumstances, individuals are recommended to undergo a colonoscopy every three years starting at an age that is 7-10 years younger than when the youngest family member with the cancer wasdiagnosed. For example, if a parent had colon cancer diagnosed at age 50, colonoscopy should start in that person's children at 40-43 years of age. (12 Dec 1998) |
| multigene family | <molecular biology> A set of genes coding for diverse proteins which, by virtue of their high degree of sequence similarity, are believed to have evolved from a single ancestral gene. An example is the immunoglobulin family where the characteristic features of the constant domains are found in various cell surface receptors. (18 Nov 1997) |
| professional-family relations | The interactions between the professional person and the family. (12 Dec 1998) |
| src-family kinases | <enzyme> Family of non-receptor protein-tyrosine kinases homologous to src. They are closely related intracellular enzymes that participate in signal transduction pathways in a variety of haemopoietic cells and especially their surface receptors. Registry number: EC 2.7.1.- (12 Dec 1998) |