| penicillin resistance | <microbiology, pharmacology> Nonsusceptibility of an organism to the action of penicillins. (12 Dec 1998) |
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| penicillin v | <chemical> (2s-(2 alpha,5 alpha,6 beta)-3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylic acid. A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms. Pharmacological action: penicillins. Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))- (12 Dec 1998) |
| penicillin V benzathine | Benzathine phenoxymethylpenicillin;penicillin for oral use. (05 Mar 2000) |
| penicillin V hydrabamine | Hydrabamine phenoxymethylpenicillin;a compound with preparation and uses analogous to those of penicillin G hydrabamine. (05 Mar 2000) |
| penicillinase | <enzyme> Penicillin amino á lactamhydrolase: an enzyme produced by certain bacteria which converts penicillin to an inactive product and thus increases resistance to the antibiotic. A purified preparation from cultures of a strain of Bacillus cereus is used in treatment of reactions to penicillin. (18 Nov 1997) |
| penicillinate | A salt of a penicillic acid (i.e., of a penicillin). (05 Mar 2000) |
| penicillins | A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. A change in the nucleus will lead to a decrease in anti-bacterial activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (goodman and gilman's the pharmacological basis of therapeutics, 8th ed, p1065) (12 Dec 1998) |
| penicilliosis | Infection with fungi of the genus Penicillium and characterised in dogs by chronic sneezing and a nasal discharge. (05 Mar 2000) |
| Penicillium | A genus of fungi (class Ascomycetes, order Aspergillales), species of which yield various antibiotic substances and biologicals; e.g., citrinum yields citrinin; Penicillium claviforme, Penicillium expansum, and Penicillium patulum yield patulin; Penicillium chrysogenum yields penicillin; Penicillium griseofulvum yields griseofulvin; Penicillium notatum yields penicillin and notatin; Penicillium cyclopium and Penicillium puberulum yield penicillic acid; Penicillium purpurogenum and Penicillium rubrum yield rubratoxin. Penicillium marneffei is a true pathogen in Southeast Asia and in the bamboo rats. Origin: see penicillus (05 Mar 2000) |
| penicillium chrysogenum | A deuteromycetous fungal species used in the production of penicillin. (12 Dec 1998) |