| RSLD | repair of sublethal damage |
|---|---|
| SLDR | sublethal damage repair |
| VVFR | vesicovaginal fistula repair |
| ABC | absolute basophil count; absolute bone conduction; acalculous biliary colic; acid balance control; a... |
| CHARGE | coloboma, heart disease, atresia choanae, retarded growth and retarded development and/or CNS anomal... |
acute angle
| DNA repair | <molecular biology> Each cell has a series of special enzymes to correct the errors in DNA structure and sequence. This protects genetic information against environmental damage and replication errors and restore the DNA to its original state. (25 Jun 1999) |
|---|---|
| DNA repair gene | A gene engaged in DNA repair. When a DNA repair gene is altered, mutations pile up throughout the DNA. (12 Dec 1998) |
| DNA repair pathway | The sequence of steps in the repair of DNA. Each step is governed by an enzyme. (12 Dec 1998) |
| error-prone repair | <molecular biology> A type of DNA repair which occurs when both nucleotides in a base pair are missing, such that it is not possible to maintain accuracy. In general, the repair proteins replace the missing nucleotides randomly. The idea is that bad DNA is better than no DNA at all. (06 Mar 1998) |
| excision repair | <molecular biology> Mechanism for the repair of environmental damage to one strand of DNA (loss of purines due to thermal fluctuations, formation of pyrimidine dimers by UV irradiation). The site of damage is recognised, excised by an endonuclease, the correct sequence is copied from the complementary strand by a polymerase and the ends of this correct sequence are joined to the rest of the strand by a ligase. The term is sometimes restricted to bacterial systems where the polymerase also acts as endonuclease. (11 Nov 1997) |
| blood patch, epidural | The injection of autologous blood into the epidural space either as a prophylactic treatment immediately following an epidural puncture or for treatment of headache as a result of an epidural puncture. (12 Dec 1998) |
| butterfly patch | Origin: Perh. From the colour of a yellow species. AS. Buter-flege, buttor-fleoge; cf. G. Butterfliege, D. Botervlieg. See Butter, and Fly. <zoology> A general name for the numerous species of diurnal Lepidoptera. See: Illust. Under Aphrodite] Asclepias butterfly. See Asclepias. Butterfly fish, a kind of double clack valve, consisting of two semicircular clappers or wings hinged to a cross rib in the pump bucket. When open it somewhat resembles a butterfly in shape. Source: Websters Dictionary (01 Mar 1998) |
| patch clamp | <physiology> A specialised and powerful variant of voltage clamping, in which a patch electrode of relatively large tip diameter (5m) is pressed tightly against the plasma membrane of a cell, forming an electrically tight, gigohm seal. The current flowing through individual ion channels can then be measured. Different variants on this technique allow different surfaces of the plasma membrane to be exposed to the bathing medium: the contact just described is a cell attached patch. If the electrode is pulled away, leaving just a small disc of plasma membrane occluding the tip of the electrode, it is called an inside out patch. If suction is applied to a cell attached patch, bursting the plasma membrane under the electrode, a whole cell patch (similar to an intracellular recording) is formed. If the electrode is withdrawn from the whole cell patch, the membrane fragments adhering to the electrode reform a seal across the tip, forming an outside out patch. (15 Mar 2000) |
| patch clamping | <physiology> A specialised and powerful variant of voltage clamping, in which a patch electrode of relatively large tip diameter (5m) is pressed tightly against the plasma membrane of a cell, forming an electrically tight, gigohm seal. The current flowing through individual ion channels can then be measured. Different variants on this technique allow different surfaces of the plasma membrane to be exposed to the bathing medium: the contact just described is a cell attached patch. If the electrode is pulled away, leaving just a small disc of plasma membrane occluding the tip of the electrode, it is called an inside out patch. If suction is applied to a cell attached patch, bursting the plasma membrane under the electrode, a whole cell patch (similar to an intracellular recording) is formed. If the electrode is withdrawn from the whole cell patch, the membrane fragments adhering to the electrode reform a seal across the tip, forming an outside out patch. (15 Mar 2000) |
| patch-clamp techniques | An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used. (15 Mar 2000) |
| patch test | A test of skin sensitiveness: a small piece of paper, tape, or a cup, wet with CO non-irritating diluted test fluid, is applied to skin of the upper back or upper outer arm and after 48 hours the area previously covered is compared with the uncovered surface; an erythematous reaction with vesicles occurs if the substance causes contact allergy. See: photo-patch test. (05 Mar 2000) |
| patch tests | Skin tests in which the sensitiser is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction. (12 Dec 1998) |
| peyer's patch | One of the lymphatic nodule aggregates existing in the intestines. (09 Oct 1997) |
| photo-patch test | A test of contact photosensitization: after application of a patch with the suspected sensitiser for 48 hours to two sites, if there is no reaction one area is exposed to a weak erythema dose of sunlight or ultraviolet light; if positive, a more severe reaction with vesiculation develops at the exposed patch area than the nonexposed skin patch site. (05 Mar 2000) |
| moth patch | <dermatology> Melasma cholasma hepaticum a term formerly used to refer to circumscribed facial hyperpigmentation resembling melasma that may occur as a cutaneous manifestation of chronic liver disease. Origin: Gr. Chloazein = to be green (18 Nov 1997) |