| critical illness polyneuropathy | A diffuse axon loss sensorimotor polyneuropathy seen in severely ill patients, usually in the intensive care unit; most patients have been on multiple drugs, and cannot be weaned from ventilatory support; electrodiagnostic studies show evidence of an axon loss polyneuropathy, predominantly motor; of unknown aetiology. (05 Mar 2000) |
|---|---|
| progressive hypertrophic polyneuropathy | A familial type of demyelinating sensorimotor polyneuropathy that begins in early childhood and is slowly progressive; clinically characterised by foot pain and paresthesias, followed by symmetrical weakness and wasting of the distal limbs; one of the causes of stork legs; patients are wheelchair bound at an early age; peripheral nerves are palpably enlarged and non-tender; pathologically, onion bulb formation is seen in the nerves: whorls of overlapping, intertwined Schwann cell processes that encircle bare axons; usually autosomal recessive inheritance. Synonym: Dejerine's disease, progressive hypertrophic polyneuropathy. (05 Mar 2000) |
| segmental demyelinating polyneuropathy | A type of polyneuropathy in which almost solely the peripheral nerve myelin is affected; can be both familial (e.g., Charcot-Marie Tooth disease, type 1), or acquired (e.g., Guillain-Barre syndrome); on motor nerve conduction studies, manifested as conduction slowing or block. Synonym: segmental demyelinating polyneuropathy. (05 Mar 2000) |
| nitrofurantoin polyneuropathy | <neurology> An axon loss polyneuropathy, often severe, seen in some patients treated with nitrofurantoin, particularly patients with chronic renal failure. (05 Mar 2000) |
| nutritional polyneuropathy | A disorder of multiple peripheral nerves, noted in beriberi, chronic alcoholism, and other clinical states, resulting from thiamin deficiency. (05 Mar 2000) |
| demyelinating polyneuropathy | A type of polyneuropathy in which almost solely the peripheral nerve myelin is affected; can be both familial (e.g., Charcot-Marie Tooth disease, type 1), or acquired (e.g., Guillain-Barre syndrome); on motor nerve conduction studies, manifested as conduction slowing or block. Synonym: segmental demyelinating polyneuropathy. (05 Mar 2000) |
| diabetic polyneuropathy | A distal, symmetrical, generally sensorimotor polyneuropathy that is a frequent complication of diabetes mellitus. (05 Mar 2000) |
| isoniazid polyneuropathy | An axonal loss polyneuropathy seen in some patients treated with isoniazid. (05 Mar 2000) |
| uraemic polyneuropathy | A distal sensory and motor polyneuropathy without conspicuous inflammation and ascribed to the metabolic effects of chronic renal failure. (05 Mar 2000) |