| pancreatic diarrhoea | Diarrhoea characterised by severe, watery, secretory diarrhoea and hyperkalaemia; most patients have hypercalcaemia, many have hyperglycaemia; results from excessive secretion of VIP (vasoactive intestinal peptide) by an islet cell tumour of the pancreas. Sometimes called WDHA syndrome. See: Verner-Morrison syndrome, WDHA syndrome. Synonym: pancreatic cholera, pancreatic diarrhoea. (05 Mar 2000) |
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| pancreatic digestion | Digestion in the intestine by the enzymes of the pancreatic juice. (05 Mar 2000) |
| pancreatic diverticula | The ventral and dorsal endodermal buds from the embryonic foregut that constitute the primordia of the parenchyma of the pancreas. (05 Mar 2000) |
| pancreatic dornase | A stabilised deoxyribonuclease preparation from beef pancreas; used by inhalation in the form of aerosols to reduce thick mucopurulent secretions in certain bronchopulmonary infections. (05 Mar 2000) |
| pancreatic duct | The excretory duct of the pancreas that extends through the gland from tail to head where it empties into the duodenum at the greater duodenal papilla. Synonym: ductus pancreaticus, Hoffmann's duct, Wirsung's canal, Wirsung's duct. (05 Mar 2000) |
| pancreatic encephalopathy | A metabolic encephalopathy associated with extensive pancreatic necrosis. (05 Mar 2000) |
| pancreatic enzyme | <biochemistry> One of the proteins made by the pancreas that aid digestion of fats, carbohydrates and proteins. (09 Oct 1997) |
| pancreatic extracts | Extracts prepared from pancreatic tissue that may contain the pancreatic enzymes or other specific uncharacterised factors or proteins with specific activities. Pancreatin is a specific extract containing digestive enzymes and used to treat pancreatic insufficiency. (12 Dec 1998) |
| pancreatic fistula | Abnormal passage communicating with the pancreas. (12 Dec 1998) |
| pancreatic function tests | Tests based on the biochemistry and physiology of the exocrine pancreas and involving analysis of blood, duodenal contents, feces, or urine for products of pancreatic secretion. (12 Dec 1998) |
| pancreatic hormones | Peptide hormones secreted into the blood by cells in the islets of langerhans of the pancreas. The alpha cells secrete glucagon; the beta cells secrete insulin; the delta cells secrete somatostatin; and the pp cells secrete pancreatic polypeptide. (12 Dec 1998) |
| pancreatic hyperglycaemic hormone | A polypeptide hormone (3485 D) secreted by the cells of the Islets of Langerhans in response to a fall in blood sugar levels. Induces hyperglycaemia. A family of structurally related peptides includes glucagon like peptides 1 & 2 (encoded by the same gene), gastric inhibitory polypeptide, secretin, vasoactive intestinal peptide, growth hormone releasing factor, pituitary adenylate cyclase activating polypeptide, exendins. (18 Nov 1997) |
| pancreatic infantilism | Infantilism associated with deficiency or absence of pancreatic secretion. (05 Mar 2000) |
| pancreatic insufficiency | Not enough of the digestive enzymes normally secreted by the pancreas into the intestine. Pancreatic insufficiency is a hallmark of cystic fibrosis. (12 Dec 1998) |
| pancreatic islands | <anatomy> Groups of cells found within the pancreas: A cells and B-cells secrete insulin and glucagon. See: D cells. (18 Nov 1997) |
| trypsin inhibitor, kazal pancreatic | <chemical> A pancreatic trypsin inhibitor common to all mammals. It is secreted with the zymogens into the pancreatic juice. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the kunitz bovine pancreatic trypsin inhibitor (aprotinin). Chemical name: Trypsin inhibitor, pancreatic secretory (12 Dec 1998) |
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| exocrine pancreatic insufficiency | Lack of exocrine secretions of pancreas, due to destruction of acini, usually by chronic pancreatitis; lack of digestive enzymes from pancreas results in diarrhoea, usually fatty (steatorrhoea) because of lack of pancreatic enzymes. (05 Mar 2000) |