| oxidative stress |
Accumulation of destructive molecules called free radicals can lead to motor neuron death. Free radicals damage components of the cells' membranes, proteins or genetic material by "oxidizing" them-the same chemical reaction that causes iron to rust. Some patients with familial ALS have mutations in the gene for superoxide dismutase type 1 (SOD1). SOD1 normally breaks down free radicals, but mutant SOD1 is unable to perform this function. ...
출처: www.als.net/als101/glossary.asp
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| oxidative stress |
A state characterized by an excess of free radical groups in the body, which creates a potentially unstable cellular environment linked to tissue damage, accelerated aging, and degenerative disease. Oxidative stress can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold, toxins, and over-exercise.
출처: www.myvits.com/html/glossary.asp
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| oxidative stress |
A process whereby the metabolic balance of a cell is disrupted by exposure to environmental substances resulting in accumulation of free-radicals, which can damage the cell.
출처: www.blindness.org/research/glossary.asp
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