| sorting out | Phenomenon observed to occur when mixed aggregates of dissimilar embryonic cell types are formed in vitro. The original aggregate sorts out so that similar cells come together into homotypic domains, usually with one cell type sorting out to form a central mass that is surrounded by the other cell type. Much controversy has arisen over the years as to the underlying mechanism, whether there is specificity in the adhesive interactions (which would imply tissue specific receptor ligand interactions) or whether it is sufficient to suppose that there are quantitative differences in homo and hetero typic adhesion (the differential adhesion hypothesis). With the exception perhaps of the main protagonists, most cell biologists consider that there are probably elements both of tissue specificity (CAMs) and of quantitative adhesive differences involved. (18 Nov 1997) |
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| stopping-out | A method adopted in etching, to keep the acid from those parts which are already sufficiently corroded, by applying varnish or other covering matter with a brush, but allowing the acid to act on the other parts. Source: Websters Dictionary (01 Mar 1998) |
| inside out patch | A variant of the patch clamp technique, in which a disc of plasma membrane covers the tip of the electrode, with the inner face of the plasma membrane facing outward, to the bath. (18 Nov 1997) |
| inside out vesicle | Mechanical disruption of cell membranes gives rise to small closed vesicles surrounded by a bilayer membrane. These may be right side out (ROV) or IOV if the topography is inverted. (18 Nov 1997) |
| out of phase | Not in phase, moving in opposite directions at the same time; 180 |
| outside out patch | A variant of patch clamp technique, in which a disc of plasma membrane covers the tip of the electrode, with the outer face of the plasma membrane facing outward, to the bath. (18 Nov 1997) |
| knock-out drops | A popular name for chloral alcoholate given with criminal intent to produce unconsciousness rapidly; it is formed by adding chloral hydrate to beer or some stronger alcoholic liquor. (05 Mar 2000) |