| nonsuppressible insulin-like activity | A blood protein (nsila) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of cohn fraction III, 10% of the activity is found in the supernatant (nsila-s) and the remaining activity in the precipitate (nsila-p). The latter is a large molecular compound, much less stable than the soluble fraction. Nsila-s is a more potent growth factor than insulin and exhibits sulfation activity. (12 Dec 1998) |
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| drug activity | A measure of the physiological response a drug produces. A less active drug produces less response (and visa versa). (12 Dec 1998) |
| insulin-like activity | A measure of substances, usually in plasma, that exert biologic effects similar to those of insulin in various bioassays; sometimes used as a measure of plasma insulin concentrations; always gives higher values than immunochemical techniques for the measurement of insulin. (05 Mar 2000) |
| intrinsic sympathomimetic activity | The property of a drug that causes activation of adrenergic receptors so as to produce effects similar to stimulation of the sympathetic nervous system. (05 Mar 2000) |
| optical activity | The ability of a material to rotate the plane of polarized light. (09 Oct 1997) |
| triggered activity | One or a series of spontaneously generated heart beats originating from an action potential that produces an after-depolarisation which reaches activation threshold. (05 Mar 2000) |
| unit of thyrotrophic activity | The activity of an amount of an extract of the anterior lobe of the hypophysis which, given daily for 5 days, will cause the thyroid of a guinea pig (weighing 200 g) to reach a weight of 600 mg. (05 Mar 2000) |
| zone of polarizing activity | <cell biology> The small group of mesenchyme cells in avian limb buds that is located at the posterior margin of the developing bud and that produces a substance, possibly retinoic acid, that provides positional information to the developing limb bud. (18 Nov 1997) |
| axis, optic | <microscopy> The direction, or directions in an anisotropic crystal along which light is not doubly refracted. (05 Aug 1998) |
| ganglionic layer of optic nerve | <anatomy, nerve> The inner layer of multipolar neurons in the retina consisting of the relatively large neurons that give rise to the fibres of the optic nerve. Synonym: stratum ganglionare nervi optici. (05 Mar 2000) |
| vascular circle of optic nerve | <anatomy, nerve> A network of branches of the short ciliary arteries on the sclera around the point of entrance of the optic nerve. Synonym: circulus vasculosus nervi optici, circulus arteriosus halleri, circulus zinnii, Haller's circle, Zinn's corona, Zinn's vascular circle. (05 Mar 2000) |
| glioma of optic chiasm | A slow-growing tumour, usually an astrocytoma, of the optic chiasm in children. (05 Mar 2000) |
| medial root of optic tract | The smaller division of the posterior end of the optic tract that disappears under the medial geniculate body. Synonym: radix medialis tractus optici. (05 Mar 2000) |
| Graves' optic neuropathy | Visual dysfunction due to optic nerve compression in Graves' orbitopathy. (05 Mar 2000) |
| pigment epithelium of optic retina | pigmented part of retina |