| oncogenesis | <oncology> The causation or production of tumours. (16 Dec 1997) |
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| proto-oncogene proteins c-mos | Cellular proteins encoded by the c-mos genes (genes, mos). They function in the cell cycle to maintain maturation-promoting factor in the active state and have protein-serine/threonine kinase activity. Oncogenic transformation can take place when c-mos proteins are expressed at the wrong time. (12 Dec 1998) |
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| proto-oncogene proteins c-myc | Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumourigenesis. (12 Dec 1998) |
| proto-oncogene proteins c-raf | <enzyme> A class of serine-threonine kinases involved in cellular signal transduction. Included in this class are the proto-oncogene proteins mil and raf. Raf is a component of a signal transduction pathway leading to increased gene expression through the c-jun DNA binding site, ap1. Registry number: EC 2.7.10.- (12 Dec 1998) |
| dominant oncogene | <genetics, molecular biology, oncology> A gene that stimulates cell proliferation and can drastically increase the risk of cancer development when present in a single copy. (09 Oct 1997) |
| immortalising oncogene | <molecular biology> A gene that upon transfectionenables a primary cell to grow indefinitely in culture. (09 Oct 1997) |
| transforming oncogene | <molecular biology> A gene that upon transfection converts a previously immortalised cell to the malignant phenotype. (09 Oct 1997) |
Synonyms : Avian Sarcoma Virus-Transforming Protein, Oncogene Protein src, Phosphoprotein pp60(v-src), Rous Sarcoma Virus-Transforming Protein pp60(v-src), p60(v-src), pp60 v-src, src Oncogene Product pp60, v-src Protein, Avian Sarcoma Virus Transforming Protein
Synonyms : Fusion Proteins, tpr met, Oncogene Protein tpr met, Protein tpr-met, Oncogene, tpr-met Fusion Proteins, tpr-met, Oncogene Protein
Synonyms : Oncogene Protein akt, v-akt Kinase Transforming Protein, Oncogene Protein v akt, akt Oncogene Protein, akt, Oncogene Protein, v akt Kinase Transforming Protein, v-akt, Oncogene Protein
Synonyms : 70Z-Cbl Protein, Casitas B-Lineage Lymphoma Protein, Oncogene Protein 70Z-Cbl, Oncogene Protein cbl, p120(cbl), v-cbl Oncogene Protein, 70Z Cbl Protein, 70Z-Cbl, Oncogene Protein, Casitas B Lineage Lymphoma Protein, Oncogene Protein 70Z Cbl
Synonyms : CT10 Regulator of Kinase Oncogene Protein, Oncogene Protein crk, v-crk Oncogene Protein, Oncogene Protein v crk, Oncogene Protein, crk, Oncogene Protein, v-crk, crk, Oncogene Protein, v crk Oncogene Protein, v-crk, Oncogene Protein
| oncogene |
A gene whose action promotes cell proliferation. Oncogenes are altered forms of proto-oncogenes.
출처: www.modernhumanorigins.com/o.html
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| oncogenesis |
Tumor (cancer) initiation in an organism.
출처: www.modernhumanorigins.com/o.html
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| oncogene |
A gene causing or contributing to cancer
출처: www.gastrolab.net/dicteo.htm
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| oncogene |
An allele of a normal gene, called a proto-oncogene, that causes a cell to become cancerous.
출처: depts.washington.edu/~genetics/courses/genet372/w2...
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| oncogene |
giving rise to tumours or causing tumour formation; genes that contribute to the formation of tumours.
출처: www.uwo.ca/pathol/glossary.html
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