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oncogenes Genes which can potentially induce neoplastic transformation. They include genes for growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. When these genes are constitutively expressed after structural and/or regulatory changes, uncontrolled cell proliferation may result. Viral oncogenes have names of the form v-onc; cellular oncogenes (proto-oncogenes) are designated c-onc.
(12 Dec 1998)
oncogenesis <oncology> The causation or production of tumours.
(16 Dec 1997)
oncogenic Causing, inducing, or being suitable for the formation and development of a neoplasm.
Synonym: oncogenic.
(05 Mar 2000)
oncogenic virus <oncology, virology> A virus capable of causing cancer in animals or in humans. These include DNA viruses, ranging in size from Papova viruses to Herpes viruses and the RNA containing retroviruses.
See: Oncovirinae.
(18 Nov 1997)
oncogenic viruses Viruses that produce tumours.
(12 Dec 1998)
oncogenous Causing, inducing, or being suitable for the formation and development of a neoplasm.
Synonym: oncogenic.
(05 Mar 2000)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 2
  • Oncogene Protein pp60(v-src) - »õâ A tyrosine-specific protein kinase encoded by the v-src oncogene of Rous sarcoma virus. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.
    Synonyms : Avian Sarcoma Virus-Transforming Protein, Oncogene Protein src, Phosphoprotein pp60(v-src), Rous Sarcoma Virus-Transforming Protein pp60(v-src), p60(v-src), pp60 v-src, src Oncogene Product pp60, v-src Protein, Avian Sarcoma Virus Transforming Protein
  • Oncogene Protein tpr-met - »õâ The GENETIC TRANSLATION product from a GENE FUSION between a sequence from the tpr protein gene on the human CHROMOSOME 1 and the gene for PROTO-ONCOGENE PROTEINS C-MET.
    Synonyms : Fusion Proteins, tpr met, Oncogene Protein tpr met, Protein tpr-met, Oncogene, tpr-met Fusion Proteins, tpr-met, Oncogene Protein
  • Oncogene Protein v-akt - »õâ A viral oncoprotein originally isolated from a murine T CELL LYMPHOMA infected with the acutely transforming retrovirus AKT8. v-akt protein is the viral homologue of PROTO-ONCOGENE PROTEINS C-AKT.
    Synonyms : Oncogene Protein akt, v-akt Kinase Transforming Protein, Oncogene Protein v akt, akt Oncogene Protein, akt, Oncogene Protein, v akt Kinase Transforming Protein, v-akt, Oncogene Protein
  • Oncogene Protein v-cbl - »õâ An oncoprotein from the Cas NS-1 murine retrovirus that induces pre- B-CELL LYMPHOMA and MYELOID LEUKEMIAS. v-cbl protein is a tyrosine-phosphorylated, truncated form of its cellular homologue, PROTO-ONCOGENE PROTEIN C-CBL.
    Synonyms : 70Z-Cbl Protein, Casitas B-Lineage Lymphoma Protein, Oncogene Protein 70Z-Cbl, Oncogene Protein cbl, p120(cbl), v-cbl Oncogene Protein, 70Z Cbl Protein, 70Z-Cbl, Oncogene Protein, Casitas B Lineage Lymphoma Protein, Oncogene Protein 70Z Cbl
  • Oncogene Protein v-crk - »õâ A signal transducing adaptor protein that is encoded by the crk ONCOGENE from TYPE C AVIAN RETROVIRUSES. It contains SRC HOMOLOGY DOMAINS and is closely related to its cellular homolog, PROTO-ONCOGENE PROTEIN C-CRK.
    Synonyms : CT10 Regulator of Kinase Oncogene Protein, Oncogene Protein crk, v-crk Oncogene Protein, Oncogene Protein v crk, Oncogene Protein, crk, Oncogene Protein, v-crk, crk, Oncogene Protein, v crk Oncogene Protein, v-crk, Oncogene Protein
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oncogenesis The progression of cytological, genetic and cellular changes that culminate in a tumour.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E18.htm
oncogenic Oncogenic genes are responsible for the transformation of normal cells into tumour cells. See Agrobacterium.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E18.htm
oncogene Any gene associated with cancer. Oncogenes are derived by the mutation of proto-oncogenes, normal cellular genes involved in growth control.
Ãâó: www.genpromag.com/Glossary~LETTER~O.html
oncogene A gene whose action promotes cell proliferation. Oncogenes are altered forms of proto-oncogenes.
Ãâó: www.modernhumanorigins.com/o.html
oncogenesis Tumor (cancer) initiation in an organism.
Ãâó: www.modernhumanorigins.com/o.html
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