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off-road motor vehicles Motorised, recreational vehicles used on non-public roads. They include all-terrain vehicles, dirt-bikes, minibikes, motorbikes, trailbikes, and snowmobiles. Excludes motorcycles, which are considered public road vehicles.
(12 Dec 1998)
on-off phenomenon A state in the treatment of Parkinson's disease by l-dopa, in which there is a rapid fluctuation of akinetic (off) and choreoathetotic (on) movements.
(05 Mar 2000)
ordered on-random off mechanism A scheme for substrate binding and product release for multisubstrate enzymes; for a two-substrate two-product enzyme with this mechanism, the individuals have to bind to the enzyme in a distinct order; however, once the products are formed they may dissociate from the enzyme in either order. It has been suggested that pyruvate kinase has such a mechanism. The random on-ordered off mechanism is simply the reverse of this mechanism.
(05 Mar 2000)
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