| SATA | spatial average, temporal average |
|---|---|
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| DSP | decreased sensory perception; delayed sleep phase; desmoplakin; dibasic sodium phosphate; digital si... |
| EPI/STAR | echo planar imaging with signal targeting and alternating radiofrequency |
| ERK | extracellular signal-regulated kinase |
| signal recognition particle | A complex between a 7S RNA and six proteins. SRP binds to the nascent polypeptide chain of eukaryotic proteins with a signal sequence and halts further translation until the ribosome becomes associated with the rough endoplasmic reticulum. One of the SRP proteins (srp54) binds GTP and in association with 7SRNA and srp19 has GTPase activity. (18 Nov 1997) |
|---|---|
| signal recognition particle receptor | Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER. (18 Nov 1997) |
| signal response coupling | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| signal sequence | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal-to-noise ratio | <microscopy> Also sometimes used as an abbreviation for serial number, can be somewhat confusing in the case of electronic equipment. (05 Aug 1998) |
| signal transduction | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| signal void | In magnetic resonance imaging, a region emitting no radiofrequency signal, either because there are no activated protons in the region (such as flowing blood) or because a different element predominates, particularly calcium. (05 Mar 2000) |
| nuclear localization signal | Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with specific receptors at nuclear pores. (12 Dec 1998) |
| atomic number | <chemistry> Symbol Z. The number of protons in the nucleus of an atom and also its characteristic atomic number. The atomic numbers of the known elements form a complete series from 1 (hydrogen) to 103 (lawrencium). (16 Dec 1997) |
| Avogadro's number | <physics> The number of molecules in a mole (gram molecular weight) of a substance, equals 6.02 x 1023 molecules. (09 Oct 1997) |
| Brinell hardness number | A number related to the size of the permanent impression made by a ball indenter of specified size (usually 10 mm in diameter) pressed into the surface of the material under a specified load: where P = applied load in kg, D = diameter of the ball in mm, and d = diameter of the impression in mm. (05 Mar 2000) |
| burst number | The number of viral particles that emerge from a cell after a viralinfection has burst it open. (09 Oct 1997) |
| Mach number | A number representing the ratio between the speed of an object moving through a fluid medium, such as air, and the speed of sound in the same medium. (05 Mar 2000) |
| magnetic mach number | <physics> A dimensionless number equal to the ratio of the velocity of a fluid to the velocity of Alfven waves in that fluid. (13 Nov 1997) |
| mass number | The mass of the atom of a particular isotope relative to hydrogen-1 (or to 1/12 the mass of carbon-12), generally very close to the whole number represented by the sum of the protons and neutrons in the atomic nucleus of the isotope (indicated in the name or symbol of the isotope; e.g., oxygen-16, 16O); not to be confused with the atomic weight of an element, which may include a number of isotopes in natural proportion. (05 Mar 2000) |