| nuclei pontis | The massive gray matter filling the basilar pons. The nuclei are of fairly homogeneous architecture and project to the cortex of the contralateral cerebellar hemisphere by way of the middle cerebellar peduncle. Their main afferents come from the entire extent of the cerebral neocortex by way of the longitudinal pontine bundles (corticopontine fibres); thus, the pontine nuclei form a major way-station in the impulse conduction from the cerebral cortex of one hemisphere to the posterior lobe of the opposite cerebellum. Synonym: nuclei pontis, pontine gray matter. (05 Mar 2000) |
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| nuclei raphes | Collections of small neurons centrally scattered among many fibres from the level of the trochlear nucleus in the midbrain to the hypoglossal area in the medulla oblongata. (12 Dec 1998) |
| nuclei tegmenti | Collective term for two small round cell groups in the caudal part of the midbrain (caudal pontine tegmental nucleus, nucleus tegmenti pontis caudalis and oral pontine tegmental nucleus, nucleus tegmenti pontis oralis), associated with the mamillary body by way of the mamillary peduncle and mamillotegmental tract. Synonym: nuclei tegmenti, Gudden's tegmental nuclei. (05 Mar 2000) |
| nuclei terminationis | Tetracyclic steroid nucleus, the group of four fused rings forming the framework or parent substance of the steroids. Synonym: perhydrocyclopenta[a]phenanthrene, steroid nucleus, terminal nuclei. (05 Mar 2000) |
| nuclei tuberales | Two or three small, encapsulated, round or ovoid clusters of cells in the lateral hypothalamic area along the surface of the tuber cinereum; their connections and functional significance are unknown. Synonym: nuclei tuberales, lateral tuberal nuclei. (05 Mar 2000) |
| nucleic acid | <biochemistry, molecular biology> Linear polymers of nucleotides, linked by 3', 5' phosphodiester linkages. In DNA, deoxyribonucleic acid, the sugar group is deoxyribose and the bases of the nucleotides adenine, guanine, thymine and cytosine. RNA, ribonucleic acid, has ribose as the sugar and uracil replaces thymine. DNA functions as a stable repository of genetic information in the form of base sequence. RNA has a similar function in some viruses but more usually serves as an informational intermediate (mRNA), a transporter of amino acids (tRNA), in a structural capacity or, in some newly discovered instances, as an enzyme. The spontaneous loss of the amino groups of cytosine (yielding uracil), methyl cytosine (yielding thymine) or of adenine (yielding hypoxanthine). It can be argued that the presence of thymine in DNA in place of the uracil of RNA stabilises genetic information against this lesion, since repair enzymes would restore the GU base pair to GC. (18 Nov 1997) |
| nucleic acid base | A purine or pyrimidine; found in naturally occurring nucleic acids such as DNA. (05 Mar 2000) |
| nucleic acid conformation | The characteristic 3-dimensional shape of a nucleic acid or polynucleotide. Its secondary structure is due to the formation of hydrogen bonds between nucleotides, resulting in base pairing and areas with alpha helix structure. (12 Dec 1998) |
| nucleic acid denaturation | Disorganization of secondary structures of nucleic acids through cleavage of hydrogen bonds and hydrophobic linkages. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. (12 Dec 1998) |
| nucleic acid heteroduplexes | Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids. (12 Dec 1998) |
| nucleic acid hybridization | Widely used technique which exploits the ability of complementary sequences in single-stranded dnas or rnas to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (kendrew, encyclopedia of molecular biology, 1994, p503; dorlands, 28th ed, p781) (12 Dec 1998) |
| nucleic acid precursors | Use for nucleic acid precursors in general or for which there is no specific heading. (12 Dec 1998) |
| nucleic acid probe | A nucleic acid fragment, labelled by a radioisotope, biotin, etc., that is complementary to a sequence in another nucleic acid (fragment) and that will, by hydrogen binding to the latter, locate or identify it and be detected; a diagnostic technique based on the fact that every species of microbe possesses some unique nucleic acid sequences which differentiate it from all others, and thus can be used as identifying markers or "fingerprints." (05 Mar 2000) |
| nucleic acid probes | Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies. (12 Dec 1998) |
| nucleic acid renaturation | The reformation of all, or part of, the native conformation of a nucleic acid molecule after the molecule has undergone denaturation. (12 Dec 1998) |
| cerebellar nuclei | Four accumulations of gray substance embedded in the white substance of the cerebellum, comprising the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii. (12 Dec 1998) |
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| reticular nuclei of the brainstem | The vaguely delineated cell groups composing the gray matter of the reticular formation of the rhombencephalon and mesencephalon. In general, large-celled territories occupy the medial two-thirds of the reticular formation: gigantocellular nucleus of medulla oblongata, nuclei tegmenti pontis caudalis and oralis. Smaller groups of reticular nuclei are found laterally and in paramedian locations; lateral nuclei receive sensory collaterals and project medially; paramedian reticular nuclei largely project to the cerebellum. See: reticular formation. (05 Mar 2000) |
| perihypoglossal nuclei | Nuclei found in the floor of the 4th ventricle in relation to the hypoglossal nucleus, includes the prepositus and intercalated nuclei and the nucleus of Roller. (05 Mar 2000) |
| Gudden's tegmental nuclei | Collective term for two small round cell groups in the caudal part of the midbrain (caudal pontine tegmental nucleus, nucleus tegmenti pontis caudalis and oral pontine tegmental nucleus, nucleus tegmenti pontis oralis), associated with the mamillary body by way of the mamillary peduncle and mamillotegmental tract. Synonym: nuclei tegmenti, Gudden's tegmental nuclei. (05 Mar 2000) |
| cochlear nuclei | The nucleus cochlearis dorsalis and nucleus cochlearis ventralis, located on the dorsal and lateral surface of the inferior cerebellar peduncle, in the floor of the lateral recess of the rhomboid fossa. They receive the incoming fibres of the cochlear part of the vestibulocochlear nerve and are the major source of origin of the lateral lemniscus or central auditory pathway. Synonym: cochlear nuclei, nuclei nervi cochlearis. (05 Mar 2000) |
| motor nuclei | Collections of motor neurons (forming a continuous column in the spinal cord, discontinuous in the medulla and pons) giving origin to the spinal and cranial motor nerves. Synonym: nuclei originis, motor nuclei. (05 Mar 2000) |
| corpus nuclei caudati | The suprathalamic part of the caudate nucleus lying in the floor of the central part of the lateral ventricle. Synonym: corpus nuclei caudati. (05 Mar 2000) |
| pontine nuclei | The massive gray matter filling the basilar pons. The nuclei are of fairly homogeneous architecture and project to the cortex of the contralateral cerebellar hemisphere by way of the middle cerebellar peduncle. Their main afferents come from the entire extent of the cerebral neocortex by way of the longitudinal pontine bundles (corticopontine fibres); thus, the pontine nuclei form a major way-station in the impulse conduction from the cerebral cortex of one hemisphere to the posterior lobe of the opposite cerebellum. Synonym: nuclei pontis, pontine gray matter. (05 Mar 2000) |
| hilum nuclei dentati | The mouth of the flasklike dentate nucleus of the cerebellum, directed inward, and giving exit to many of the fibres which compose the superior cerebellar peduncle or brachium conjunctivum. Synonym: hilum nuclei dentati. (05 Mar 2000) |
| hilum nuclei olivaris | The medially oriented opening in the folded cell layer composing the inferior olivary nucleus through which the efferent fibres of the nucleus make their exit. Synonym: hilum nuclei olivaris. (05 Mar 2000) |
| secondary sensory nuclei | Nuclei terminales, collective term indicating those nerve cell groups in the rhombencephalon and spinal cord in which the afferent fibres of the spinal and cranial nerves terminate. Synonym: nuclei terminationis, secondary sensory nuclei. (05 Mar 2000) |
| sensory nuclei | A group of cell bodies that receive afferent (sensory) input from the periphery. (05 Mar 2000) |
| septal nuclei | Neural nuclei situated in the septal region of the diencephalon. (12 Dec 1998) |
| sole nuclei | An accumulation of skeletal muscle fibre nuclei at the myoneural junction. (05 Mar 2000) |
| somatic motor nuclei | Collective term indicating the motor nuclei innervating the tongue musculature (hypoglossal nucleus) and the extraocular eye muscles (abducens nucleu, trochlear nucleus, and oculomotor nucleus). (05 Mar 2000) |
Synonyms : Acid Precursors, Nucleic, Precursors, Nucleic Acid
Synonyms : Acid Probes, Nucleic, Probes, Nucleic Acid
Synonyms : Acid Renaturation, Nucleic, Acid Renaturations, Nucleic, Nucleic Acid Renaturations, Renaturation, Nucleic Acid, Renaturations, Nucleic Acid
Synonyms : Inhibitors, DNA Synthesis, Inhibitors, Nucleic Acid Synthesis, Inhibitors, RNA Synthesis, Synthesis Inhibitors, DNA, Synthesis Inhibitors, RNA
Synonyms : Acids, Nucleic
| nucleic acid |
Organic substance, found in all living cells, in which the hereditary information is stored and from which it can be transferred. Nucleic acid molecules are long chains that generally occur in combination with proteins. The two chief types are DNA (deoxyribonucleic acid), found mainly in cell nuclei, and RNA (ribonucleic acid), found mostly in cytoplasm.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
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| nucleic acid |
A molecule of very high molecular weight used to store and process the genetic information in cells.
Ãâó: xenon.che.ilstu.edu/genchemhelphomepage/glossary/n...
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| nuclei |
Plural of nucleus.
Ãâó: dictionary.rare-cancer.org/dictionary.php
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| nucleic acid |
A polymer of nucleotides, see also DNA and RNA.
Ãâó: www.hardydiagnostics.com/Glossary-N.html
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| nucleic acid |
Description: A biological molecule composed of a long chain of nucleotides. DNA is made of thousands of four different nucleotides repeated randomly. Source: Specialized encyclopedia and dictionaries
Ãâó: europa.eu.int/comm/research/biosociety/library/glo...
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