| EDS | edema disease of swine; egg drop syndrome; Ehlers-Danlos syndrome; Emery-Dreifus syndrome; energy-di... |
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| EMSA | electrophoretic mobility shift assay |
| LSR | lanthanide shift reagent; lecithin/ sphingomyelin ratio; left superior rectus [muscle]; liver/spleen... |
| MS | Maffuci syndrome; maladjustment score; mandibular series; Marfan syndrome; Marie-Strumpell [syndrome... |
| NIPTS | noise-induced permanent threshold shift |
| threshold shift | Measurement of the degree of hearing loss or impairment in terms of a decibel shift from an individual's previous audiogram. (05 Mar 2000) |
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| ym-shift | <microbiology> The change in shape by dimorphic fungi when they shift from the yeast (Y) form in the animal body to the mould or mycelial form (M) in the environment. (09 Oct 1997) |
| luteoplacental shift | The change in site of production of the oestrogen and progesterone essential for human pregnancy from the corpus luteum to the placenta; ovariectomy always terminates pregnancy in most mammals because their placentas never produce enough oestrogen and progesterone, but, after the sixth week of pregnancy, a human placenta can produce enough of these hormones to prevent abortion despite ovariectomy. (05 Mar 2000) |
| receptors, cytoplasmic and nuclear | Proteins in the cytoplasm or nucleus that specifically bind signalling molecules and trigger changes which influence the behaviour of cells. The major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus. Receptors, unlike enzymes, generally do not catalyze chemical changes in their ligands. (12 Dec 1998) |
| Remak's nuclear division | <cell biology> An unusual form of nuclear division, in which the nucleus simply constricts, rather like a cell without chromosome condensation or spindle formation. Partitioning of daughter chromosomes is haphazard. Observed in some Protozoa. (18 Nov 1997) |
| Pelger-Huet nuclear anomaly | Congenital inhibition of lobulation in the nuclei of neutrophilic leukocytes; most cells present band or bilobulate appearance, and only an occasional cell is trilobed; it is not associated with disease, but may be confused with leukocyte "shift to left"; autosomal dominant inheritance. (05 Mar 2000) |
| ribonucleoproteins, small nuclear | Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end processing in the nucleoplasm. The u3 snrnp is localised in the nucleolus, where it aligns into base pairs with the 28s rrna precursor in a still unidentified region and functions in pre-rrna processing. The u7 snrnp aligns into base pairs with a conserved sequence in the 3'-end of histone pre-mRNA and is an essential cofactor for the cleavage that creates the mature nonadenylated 3'-end. (12 Dec 1998) |
| RNA, heterogeneous nuclear | Nuclear nonribosomal RNA larger than about 1000 nucleotides, the mass of which is rapidly synthesised and degraded within the cell nucleus. Some heterogeneous nuclear RNA may be a precursor to mRNA. However, the great bulk of total hnrna hybridises with nuclear DNA rather than with mRNA. (12 Dec 1998) |
| RNA, nuclear | RNA molecules found in the nucleus either associated with chromosomes or in the nucleoplasm. (12 Dec 1998) |
| RNA, small nuclear | Short chains of RNA found in the nucleus. Their function is to remove the introns (nontranslated intervening sequences) from mRNA precursors, thereby bringing the two exons (coding segments) together into correct juxtaposition for enzymatic splicing at the correct point. The resulting mRNA is now ready to leave the nucleus. (12 Dec 1998) |
| rod nuclear cell | <pathology> Immature neutrophils released from the bone marrow reserve in response to acute demand. (18 Nov 1997) |
| cistern of nuclear envelope | The space between the internal and external membranes of the nuclear envelope; may be continuous in places with cisterns of the endoplasmic reticulum. Synonym: cistern of nuclear envelope, perinuclear space. (05 Mar 2000) |
| proliferating cell nuclear antigen | Acidic nuclear protein (33 kD) highly expressed in dividing cells. Interacts with D type cyclins. (18 Nov 1997) |
| heterogeneous nuclear RNA | An ill-defined form of RNA, of high molecular weight, that never leaves the nucleus and is thought to be the precursor of messenger RNA. (05 Mar 2000) |
| heterogenous nuclear RNA | <molecular biology> Originally identified as a class of RNA, found in the nucleus but not the nucleolus, which is rapidly labelled and with a very wide range of sizes, 2-40 kilobases. It represents the primary transcripts of RNA polymerase II and includes precursors of all messenger RNAs from which introns are removed by splicing. (18 Nov 1997) |