| reverse mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
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| chromosomal mutation | Can refer to any of a number of DNA mutations which results in a change in the protein encoded by the mutated gene, such as point mutations, insertion or deletion mutations (frameshift mutations), or nonsense mutations. More often this refers to mutations involving chromosomes, such as the inversion of part of one chromosome such that the inverted part no longer matches with its homologous pair, a translocation of one part of a chromosome to a different chromosome, deletions of parts of chromosomes, or accidents which happen during the division of the nucleus like the unequal portioning of chromosomes between the daughter cells. (09 Oct 1997) |
| missense mutation | <molecular biology> A mutation that alters a codon for a particular amino acid to one specifying a different amino acid. (18 Nov 1997) |
| conditional mutation | <molecular biology> A mutation that is only expressed under certain environmental conditions for example temperature sensitive mutants. (05 Jan 1998) |
| point mutation | <molecular biology> Mutation that causes the replacement of a single base pair with another pair. (18 Nov 1997) |
| polar mutation | <molecular biology> A mutation in a single gene which affects the rate of expression of other genes that are near it on a chromosome. (09 Oct 1997) |
| mutation | 1. A change in form, quality or some other characteristic. 2. <genetics> A permanent transmissible change in the genetic material, usually in a single gene. Also, an individual exhibiting such a change. Also called (in classical genetics) a sport. Origin: L. Mutatio from mutare = to change (18 Nov 1997) |
| mutation rate | The frequency with which a particular mutation appears in a population or the frequency with which any mutation appears in the whole genome of a population. Normally the context makes the precise use clear. See: fluctuation analysis. (18 Nov 1997) |
| private mutation | A rare mutation found usually only in a single family or a small population. It is like a privately printed book. (12 Dec 1998) |
| hereditary mutation | A gene change that occurs in a germ cell (an egg or sperm) to become incorporated in every cell in the body. Hereditary mutations (also called germline mutations) play a role in cancer as, for example, the eye tumour retinoblastoma and wilms' tumour of the kidney. (12 Dec 1998) |
| homeotic mutation | <embryology, genetics> A mutation that causes an organism to develop a homologous body part or structure in place of the part or structure that should normally be there (for example, developing a hand in place of a foot). (09 Oct 1997) |
| silent mutation | Mutations that have no effect on phenotype because they do not affect the activity of the product of the gene, usually because of codon ambiguity. (18 Nov 1997) |
| site specific mutation | An alteration of the structure of a gene at a specific sequence, usually referring to experimentally produced changes in gene sequence. (05 Mar 2000) |
| somatic mutation | Mutation that occurs in the somatic tissues of an organism and that will not, therefore, be heritable, since it is not present in the germ line. Some neoplasia is due to somatic mutation, a more conspicuous example is the reversion of some branches of variegated shrubs to the wild type (completely green) phenotype. Somatic mutation is probably also important in generating diversity in V gene regions of immunoglobulins. (18 Nov 1997) |
| somatic mutation theory of cancer | That cancer is caused by a mutation or mutations in the body cells (as opposed to germ cells), especially nonlethal mutations associated with increased proliferation of the mutant cells. (05 Mar 2000) |
| nonsense mutation |
A defect in the gene that results in the loss of a letter in the code that usually alters the formation of its protein product. Thus, a nonsense mutation can lead to a shorter enzyme missing its most important parts for proper function.
출처: www.lsdn.com/glance_glossary.shtml
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| nonsense mutation |
A type of mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein.
출처: www.bscs.org/onco/glossary.htm
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| nonsense mutation |
is any change in DNA that causes a (termination) codon to replace a codon representing an amino acid.
출처: www.hgsc.bcm.tmc.edu/docs/HGSC_glossary.html
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| nonsense mutation |
a mutation that alters a codon such that it no longer codes for an amino acid but instead codes for a stop signal (a signal that tells the protein-making machinery to stop making protein)
출처: www-hsc.usc.edu/~dconti/notes/genetic_terms.htm
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| nonsense mutation |
A mutation that alters a gene so as to produce a .
출처: ai.ia.ac.cn/helios.bto.ed.ac.uk/bto/glossary/no.ht...
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