| new mutation | Redundant term for a heritable trait present in the offspring but in neither parent, i.e., not a pre-existing mutant form inherited. (05 Mar 2000) |
|---|---|
| new south wales | A state in southeastern Australia. Its capital is sydney. It was discovered by captain cook in 1770 and first settled at botany bay by marines and convicts in 1788. It was named by captain cook who thought its coastline resembled that of south wales. (12 Dec 1998) |
| New World leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| acridine yellow | A faintly yellow solution with strong bluish-violet fluorescence; used as a topical antiseptic and as a fluorescent stain in histology. Synonym: 5-aminoacridine hydrochloride, 9-aminoacridine hydrochloride. (05 Mar 2000) |
| acute yellow atrophy of the liver | A lesion in which there is extensive and rapid death of parenchymal cells of the liver, sometimes with fatty degeneration of the size of the organ; the necrosis may result from fulminant viral infection or chemical poisoning; associated with jaundice. Synonym: acute parenchymatous hepatitis, Rokitansky's disease. (05 Mar 2000) |
| brilliant yellow | An indicator dye that changes from yellow to orange or red at pH 6.4 to 8.0. (05 Mar 2000) |
| butter yellow | C6H5N:NC6H4N(CH3)2;a fat-soluble yellow dye (MW 225) that has hepatic carcinogenic action in experimental animals; used as an indicator of pH (red, at pH 2.9, yellow at pH 4.0). Synonym: dimethylaminoazobenzene, methyl yellow. (05 Mar 2000) |
| martius yellow | C10H6N2O5; 2,4-dinitro-alpha-naphthol;an acid dye used as a plasma stain in plant and animal histology, and as a light filter for photomicrography. Origin: Karl A. Martius, Ger. Chemist, *1920 (05 Mar 2000) |
| Paris yellow | A fine yellow powder used in paints and dyes. Synonym: lead chromate, Leipzig yellow, lemon yellow, Paris yellow. (05 Mar 2000) |
| visual yellow | The orange retinaldehyde resulting from the action of light on the rhodopsin of the retina, which converts the 11-cis-retinal component of the rhodopsin to all-trans-retinal plus opsin. Synonym: trans-retinal, visual yellow. (05 Mar 2000) |