| ANDA | Abbreviated New Drug Application |
|---|---|
| IND | indomethacin; industrial medicine; investigational new drug |
| NAD | neutrophil actin dysfunction; new antigenic determinant; nicotinamide adenine dinucleotide; nicotini... |
| NADA | New Animal Drug Application |
| NCE | negative contrast echocardiography; new chemical entity; nonconvulsive epilepsy |
| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
|---|---|
| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| anterior nuclei of thalamus | Collective term for three groups of nerve cells which together form the anterior thalamic tubercle: the anteroventral nuclei, a relatively large nucleus; the anteromedial nuclei; and the anterodorsal nuclei, a small (but large-celled) nucleus. The nuclei receive the mamillothalamic tract from the mamillary body, and additional afferents by way of the fornix; they project collectively to the cortex of the cingulate and parahippocampal gyrus. Synonym: nuclei anteriores thalami. (05 Mar 2000) |
| anterior tubercle of thalamus | anterior thalamic tubercle |
| arcuate nucleus of thalamus | The small ventral region of the ventral posteromedial nucleus of thalamus in which the fibres of the gustatory lemniscus and secondary trigeminal tracts terminate; it projects to the lower part of the postcentral gyrus of the cerebral cortex. Synonym: arcuate nucleus, nucleus arcuatus thalami, nucleus arcuatus, semilunar nucleus of Flechsig, thalamic gustatory nucleus. (05 Mar 2000) |
| paracentral nucleus of thalamus | One of the intralaminar nuclei of the thalamus, medial to the central lateral nucleus. Synonym: nucleus paracentralis thalami. (05 Mar 2000) |
| ventral anterior nucleus of thalamus | The most rostral of the subdivisions of the ventral nucleus, receiving projections from the globus pallidus and projecting to the premotor and frontal cortex. Synonym: nucleus ventralis anterior thalami. (05 Mar 2000) |
| ventral intermediate nucleus of thalamus | The composite middle third of the ventral nucleus receiving in its various parts distinctive projections from the contralateral half of the cerebellum (by way of the superior cerebellar peduncle) and the ipsilateral globus pallidus; nearly all parts of the nucleus projects to the motor cortex. Synonym: nucleus ventralis intermedius thalami, nucleus ventralis lateralis, ventral lateral nucleus of thalamus. (05 Mar 2000) |
| ventral lateral nucleus of thalamus | The composite middle third of the ventral nucleus receiving in its various parts distinctive projections from the contralateral half of the cerebellum (by way of the superior cerebellar peduncle) and the ipsilateral globus pallidus; nearly all parts of the nucleus projects to the motor cortex. Synonym: nucleus ventralis intermedius thalami, nucleus ventralis lateralis, ventral lateral nucleus of thalamus. (05 Mar 2000) |
| ventral nucleus of thalamus | A large, complex cell mass the external border of which forms the ventral and much of the lateral boundary, as well as the rostral border, of the thalamus; it can be subdivided into an anterior, intermediate, and posterior part. Synonym: nucleus ventralis thalami. (05 Mar 2000) |
| ventral posterior intermediate nucleus of thalamus | Intermediate part of the ventrobasal nuclear complex. See: ventral posterior nucleus of thalamus. Synonym: ventral posterior intermediate nucleus of thalamus. (05 Mar 2000) |