| EF | ectopic focus; edema factor; ejection fraction; elastic fibril; electric field; elongation factor; e... |
|---|---|
| PF | pair feeding; peak flow; perfusion fluid; pericardial fluid; periosteal fibroblast; peritoneal fluid... |
| ENA | epithelial neutrophil-activating [protein]; extractable nuclear antigen |
| RAS | rapid atrial stimulation; recurrent aphthous stomatitis; reflex activating stimulus; reliability, av... |
| SF | Sabin-Feldman [test]; safety factor; salt-free; scarlet fever; screen film; seminal fluid; serosal f... |
| neutrophil activation | The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonised particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil. (12 Dec 1998) |
|---|---|
| neutrophil collagenase | <enzyme> Cleaves interstitial collagens in the triple helical domain; cleaves type I collagen more rapidly than type III; fibroblast collagenase cleaves at the same site as neutrophil colagenase Registry number: EC 3.4.24.34 Synonym: matrix metalloproteinase 8, mmp-8, mmp 8, fibroblast collagenase (26 Jun 1999) |
| neutrophil granule | A granule stainable with the neutral component of stains, e.g., the Romanovsky-type blood stains. (05 Mar 2000) |
| acetyl-activating enzyme | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acyl-activating enzyme | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| amino acid activating enzyme | <enzyme> Enzymes catalyzing the formation of a specific aminoacyl-tRNA from an amino acid and adenosine 5'-triphosphate with the concomitant formation of adenosine 5'-monophosphate and pyrophosphate. Synonym: amino acid activating enzyme, aminoacyl-tRNA ligases. (05 Mar 2000) |
| p53-activating kinase | <enzyme> Regulates p53 activity in saccharomyces cerevisiae; 810 amino acid residues; genbank u24167; do not confuse with pak I, protease-activated kinase Registry number: EC 2.7.10.- Synonym: pak1 gene product, yeast pak1 (26 Jun 1999) |
| pantoate-activating enzyme | pantothenate synthetase |
| virus activating protease | <enzyme> Endoprotease from chick embryo; activates para- and orthomyoxovirus fusion glycoproteins by cleaving them at a single arginine site; ca(2+) dependent; similar to blood clotting factor x Registry number: EC 3.4.21.- (26 Jun 1999) |
| reticular activating system | <physiology> A physiological term denoting that part of the brainstem reticular formation that plays a central role in the organism's bodily and behavorial alertness. It extends as a diffusely organised neural apparatus through the central region of the brainstem into the subthalamus and the intralaminar nuclei of the thalamus; by its ascending connections it affects the function of the cerebral cortex in the sense of behavioural responsiveness; its descending (reticulospinal) connections transmit its activating influence upon bodily posture and reflex mechanisms (e.g., muscle tonus), in part by way of the gamma motor neurons. See: reticular formation. Synonym: non-specific system. (05 Mar 2000) |
| GTPase activating protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
| methionine-activating enzyme | <enzyme> An enzyme that catalyses the synthesis of s-adenosylmethionine from methionine and ATP. Chemical name: ATP:L-methionine S-adenosyltransferase Registry number: EC 2.5.1.6 (12 Dec 1998) |
| complement activating enzymes | <enzyme> Enzymes present in the complement system which activate one or more components in the system. Registry number: EC 3.- (12 Dec 1998) |
| connective tissue activating peptide III | Cytokine, produced from platelet basic protein, that acts as a growth factor. (18 Nov 1997) |
| JNK-activating protein kinase | <enzyme> A dual specificity kinase that activates jun kinases and p38-mpk2; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: jnk kinase, jnkk, hemipterous protein, hep protein, jun amino-terminal kinase kinase, jn kinase kinase, hep gene product (26 Jun 1999) |