| 영문 | cranial nerve | 한글 | 뇌신경 |
|---|---|---|---|
| 설명 | 대부분의 신경은 척수를 통해서 나간다. 그러나 몇몇의 신경은 뇌에서 바로 나간다. 이렇게 뇌에서 바로 나가는 신경을 뇌신경이라고 한다. 이 뇌신경은 12개로 모두 대칭적인 쌍으로 존재한다. 이 뇌신경은 주로 특수감각(시각, 청각, 후각, 미각)과 얼굴 등의 일부 근육을 지배하고 심장이나 내장의 지배도 일부 담당하고 있다. 12개의 신경은 각각 다음과 같은 이름과 고유번호를 가지고 있다. -후각신경(olfactory nerve)－후각을 담당하는 신경, -시각신경(optic nerve)－시각을 담당하는 신경. -눈돌림신경(oculomotor nerve)－운동을 담당하는 신경, -도르래신경(trochlear nerve)－눈의 운동을 담당하는 신경. -삼차신경(trigeminal nerve)－3개의 가지를 가지는 신경으로 얼굴의 감각과 씹기를 위한 근육을 움직이는 역할을 한다. -가돌림신경(abducent nerve)－눈의 운동을 담당하는 신경. -얼굴신경(facial nerve)－얼굴 근육의 운동을 담당하는 신경. 즉 얼굴이 여러 가지 표정을 내는 것은 이 신경의 작용이다. 그리고 혀의 앞부분의 미각을 담당하는 역할도 한다. -안뜰달팽이신경(vestibulocochlear nerve)－안뜰신경과 달팽이신경의 2가지 신경으로 이루어진 신경으로 모두 귀를 지배하는 신경이다. 안뜰신경은 평형감각을 담당하는 곳인 귀의 안뜰에서 나오는 신경으로 평형감각의 정보를 뇌에 전하는 역할을 한다. 그리고 달팽이신경은 청각을 감지하는 달팽이껍질의 모양을 가진 달팽이에서 기원하는 신경으로 청각의 정보를 뇌에 전달하는 역할을 한다. -혀인두신경(glossopharyngeal nerve)－말 그대로 혀와 인두부에 분포하는 신경으로 인후부의 움직임과 혀의 뒷부분의 미각을 담당한다. -미주신경(vagus nerve)－말 그대로 아주 여러 곳에 분포하여 분포영역이 모호한 신경이다(vagus란 모호한 이란 뜻을 가진다). 대부분의 내장에 분포하고 또 심장에 분포하여 심장의 박동수를 조정하는 역할도 한다. -더부신경(accessory nerve)－등의 근육과 목의 근육의 일부를 지배하는 신경. -혀밑신경(hypoglossal nerve)－혀의 움직임을 관장하는 신경. |
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| 영문 | afferent nerve | 한글 | 들신경 |
|---|---|---|---|
| 설명 | 몸의 중심으로 들어오는 신경, 즉 감각신경을 지칭하는 말이다. |
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| 영문 | peripheral nerve | 한글 | 말초신경 |
|---|---|---|---|
| 설명 | 중추신경계를 제외한 나머지 모든신경을 말함. 중추신경계는 뇌와 척수를 말하며, 그외 나머지 신경들로써 실제적으로 각 기관이나 사지 말단에 신경이 분포하며, 자극을 전달하는 일을 하는 신경을 모두 통틀어 말초신경이라 한다. 뇌에서 바로 나와 분포하는 뇌신경과 척수에서 기시하는 척수신경도 모두 말초신경에 해당한다. 또한 말초신경에는 각종 자율신경을 담당하는 교감신경, 부교감신경도 포함된다. |
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| 영문 | vagus nerve | 한글 | 미주신경 |
|---|---|---|---|
| 설명 | 제 10뇌신경(뇌신경은 뇌에서 기시한 말초신경으로 모두 12개가 있다)의 이름. 올리브와 아래소뇌각(inferior cerebellopontine angle)사이 숨뇌 외측에서 나오는 많은 뿌리섬유로부터 기시하여 상후두신경, 되돌이후두신경, 경질막가지, 귀바퀴가지, 인두가지, 심장가지, 기관지인지, 위가지, 간가지, 복강가지, 콩팥가지, 인두신경얼기(pharyngeal plexus), 폐신경얼기(pulmonic plexus), 식도신경얼기(esophageal plexus), 전 및 후 미주신경간(anterior & posterior vagal trunk)의 가지를 낸다. 미주신경은 목정맥구멍(jugular foramen)을 통해 내려가서 상하신경절(superior & inferior ganglion)과 연결되고, 목 및 가슴를 지나 복부에 도달한다. 귀, 혀, 인두, 후두에 감각성으로, 인두, 후두 및 식도에 운동성으로, 그리고 흉부 및 복부의 기관에 내장구심성으로 분포한다.  |
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| 영문 | optic nerve | 한글 | 시각신경 |
|---|---|---|---|
| 설명 | 시각을 인지하는 신경. 이 신경은 단지 감각신경으로서만 작용한다. 따라서 어떤 사물을 따라 눈을 움직일 수 있는 것은 이 시각신경과는 무관하다(이것은 눈돌림신경(oculomotor nerve)에 의해 가능하다). 또한 시각신경은 고위중추신경계인 뇌에서 직접 분지하므로 손상시 재생은 불가능하며, 이에 대한 치료법은 없다. |
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| GF | gastric fistula; gastric fluid; germ-free; glass factor; glomerular filtration; gluten-free; grandfa... |
|---|---|
| SGF | sarcoma growth factor; skeletal growth factor |
| PAF | paroxysmal atrial fibrillation; peroxisomal assembly factor; phosphodiesterase-activating factor; pl... |
| SF | Sabin-Feldman [test]; safety factor; salt-free; scarlet fever; screen film; seminal fluid; serosal f... |
| TF | free thyroxine; tactile fremitus; tail flick [reflex]; temperature factor; testicular feminization; ... |
| receptors, growth factor | Cell surface receptors that bind growth or trophic factors with high affinity, triggering intracellular responses which influence the growth, differentiation, or survival of cells. (12 Dec 1998) |
|---|---|
| receptors, insulin-like-growth factor I | Specific proteins on or in cells to which insulin-like growth factor I (somatomedin c) binds and thereby modifies the function of the cells. These receptors contain transmembrane and cytosolic domains, bind igf-I preferentially, and have high-affinity sites for igf-II. The alpha-subunit has a mw of 130 kD and the beta subunit possesses tyrosine kinase activity. (12 Dec 1998) |
| receptors, insulin-like-growth-factor II | Specific proteins on or in cells to which insulin-like growth factor II and mannose-6-phosphate bind and thereby modify the function of the cells. These receptors have a mw of 250 kD and possess no tyrosine kinase activity. (12 Dec 1998) |
| receptors, platelet-derived growth factor | Specific molecular sites or structures on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists, to elicit or to inhibit the specific response of the cell to this factor. Pdgf binds with different affinities and specificities to two structurally related receptors, the alpha-receptor and the beta-receptor. Both of these receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein kinase domain. (12 Dec 1998) |
| receptors, transforming growth factor beta | Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the behaviour of cells. Two types of transforming growth factor receptors have been recognised. They differ in affinity for different members of the transforming growth factor beta family and in cellular mechanisms of action. Transforming growth factor alpha binds to the same receptors as epidermal growth factor (see receptors, epidermal growth factor-urogastrone). (12 Dec 1998) |
| growth factor | <biochemistry> A complex family of polypeptide hormones or biological factors that are produced by the body to control growth, division and maturation of blood cells by the bone marrow. They regulate the division and proliferation of cells and influence the growth rate of some cancers. These factors occur naturally but some can be synthesised using molecular biology techniques and are used clinically to stimulate normal white cell production following chemotherapy or bone marrow transplantation. Examples include epidermal growth factor, platelet-derived growth factor, fibroblast growth factor. Insulin and somatomedin are also growth factors, the status of nerve growth factor is more uncertain. Perturbation of growth factor production or of the response to growth factor is important in neoplastic transformation. (29 Sep 1997) |
| growth hormone-releasing factor | <endocrinology> Peptide hormone related to the glucagon family, released from the pituitary, acts on the adenohypophysis to release growth hormone. Synonym: somatoliberin, growth hormone-releasing factor. (20 Sep 2002) |
| platelet-derived growth factor | <growth factor> The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. Believed to play a role in wound healing. It is carried in the alpha-granules of platelets and is released when platelets adhere to traumatised tissues. Connective tissue cells near the traumatised region respond by initiating the process of replication. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus, that can transform only those cells that express receptors for platelet derived growth factor, suggesting that transformation is caused by autocrine stimulation. The receptor is a tyrosine kinase. Acronym: PDGF (12 Dec 1998) |
| sarcoma growth factor | <growth factor> Polypeptide released by sarcoma cells that promotes the growth of cells by binding to a cell surface receptor, the sarcoma cell is therefore self sufficient and independent of normal growth control. See: growth factors. The name is no longer commonly used. (18 Nov 1997) |
| heparin binding growth factor | <growth factor> Acidic fibroblast growth factor (alpha FGF, HBGF 1) and basic FGF (beta FGF, HBGF 2) are the two founder members of a family of structurally related growth factors for mesodermal or neuroectodermal cells. Synonym: heparin binding growth factor. Acronym: FGF (18 Nov 1997) |
| hepatocyte growth factor | <growth factor> Polypeptide mitogen originally shown to cause cell division in hepatocytes. In the liver, the main sources of hepatocyte growth factor are nonparenchymal cells. It is now clear that hepatocyte growth factor is a mitogen for a number of cell types and it is found in many cells outside the liver, including platelets. Hepatocyte growth factor is synthesised as a single chain precursor that is proteolytically cleaved to give a heavy chain (70 kD) and a light chain (30 kD) linked by a single disulphide bond. It contains multiple copies of the kringle domain. However, both the single chain precursor and the two chain forms of hepatocyte growth factor are biologically active and hepatocyte growth factor is generally isolated as a mixture of the two forms. Hepatocyte growth factor also alters cell motility and is now known to be identical to scatter factor. Acronym: HGF (18 Nov 1997) |
| pro-transforming growth factor-alpha processing protease | <enzyme> Converts membrane-bound protgf-alpha to soluble tgf-alpha; mw 84 kD Registry number: EC 3.4.21.- Synonym: protgf-alpha converting enzyme, protgfalpha processing protease (26 Jun 1999) |
| schwannoma derived growth factor | <growth factor> A growth factor containing an EGF like domain, mitogenic for astrocytes, Schwann cells and fibroblasts. (18 Nov 1997) |
| insulin like growth factor | <growth factor> Insulin like growth factors I and II are polypeptides with considerable sequence similarity to insulin. They are capable of eliciting the same biological responses, including mitogenesis in cell culture. On the cell surface, there are two types of insulin like growth factor receptor, one of which closely resembles the insulin receptor (which is also present). Insulin like growth factor I = somatomedin A = somatomedin C Insulin like growth factor II = MSA (Multiplication stimulating activity). Insulin like growth factor 1 is released from the liver in response to growth hormone. Acronym: IGF (18 Nov 1997) |
| insulin-like growth-factor binding protein 1 | One of the six homologous proteins that specifically bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits igf binding to cell surface receptors and thereby inhibits igf-mediated mitogenic and cell metabolic actions. (proc soc exp biol med 1993;204(1):4-29) (12 Dec 1998) |