| 영문 | tissue biopsy | 한글 | 조직생검 |
|---|---|---|---|
| 설명 | 환자의 병적인 조직의 일부를 떼어 내서 병리조직표본을 만들어서 현미경적으로 검사하는 것. 외과적 수술재료로부터 병리조직학적 검사를 하여 생체내의 병변을 추구하는 분야를 외과병리학이라고 한다. 생검에는 쐐기생검, 천자침생검, 꿰뚫기식생검, 내시경생검 외에 세포진이라고 불리우는 박리세포진이나 세척세포진 등 떨어진 세포를 도말검사하는 방법이 포함된다. |
||
| 영문 | target tissue | 한글 | 표적조직 |
|---|---|---|---|
| 설명 | 호르몬에 대하여 표적이 되는 세포라는 의미로서 그 호르몬에 대한 수용체를 가지고 있는 세포. 예를 들어 인슐린은 인슐린 수용체를 가진 세포를 표적세포로 하여 이 세포에만 작용한다. |
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| 영문 | subcutaneous tissue, subcutis | 한글 | 피하조직 |
|---|---|---|---|
| 설명 | 피부에서 진피의 아랫부분을 말함. 여기에는 지방조직이 많다. 기능은 열의 격리, 충격흡수, 영양저장소 등이다. |
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| GDXY | XY gonadal dysgenesis |
|---|---|
| GSBG | gonadal steroid-binding globulin |
| MGD | maximal glucose disposal; mixed gonadal dysgenesis |
| ABCDES | abnormal alignment, bones-periarticular osteoporosis, cartilage-joint space loss, deformities, margi... |
| TCID | tissue culture infective dose; tissue culture inoculated dose |
| gonadal dysgenesis | <embryology, genetics> A rare genetic disorder in women that is characterised by the absence of an X chromosome. This disorder inhibits normal sexual development and causes infertility. Features include webbing of the neck, short stature, retarded development of secondary sex characteristics, absence of menses, coarctation of the aorta, low hairline, eye abnormalities (drooping eyelids) and skeletal deformities. Treatment include oestrogen supplementation at puberty. Growth hormone replacement may be necessary in some cases. Cardiac surgery may be necessary to correct coarctation of the aorta. Incidence: 1 in 3,000 births. (10 Oct 1997) |
|---|---|
| gonadal dysgenesis, 46,xy | A syndrome characterised by "streak gonads" in a phenotypic female with a 46,xy karyotype. It is due to a mutation which inhibits the function of the y-borne determinant that would normally cause the indifferent embryonic gonad to differentiate into a testis. The streak gonad is incapable of ovulation or oestrogen secretion. The syndrome is sometimes called "pure gonadal dysgenesis," but this designation may also refer to the presence of streak gonads with a 46,xx karyotype. (12 Dec 1998) |
| gonadal dysgenesis, mixed | A syndrome of gonadal dysgenesis in which there is a testis on one side and a "streak gonad" on the other. The phenotype is generally male, but may be female since the individual is a mosaic. Various karyotypes have been identified, including 45,xo/47,xyy; 45,xo/46,xy; and 45,xo/46,xyo. (12 Dec 1998) |
| gonadal hormones | Hormones having oestrogenic (female sex hormones) or androgenic (male sex hormones) activity. (12 Dec 1998) |
| gonadal ridge | An elevation of thickened mesothelium and underlying mesenchyme on the ventromedial border of the embryonic mesonephros; the primordial germ cells become embedded in it, establishing it as the primordium of the testis or ovary. Synonym: genital ridge. (05 Mar 2000) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| gonadal streak | A form of aplasia in which the ovary is replaced by a functionless tissue, as found in Turner's syndrome. Synonym: streak gonad. (05 Mar 2000) |
| sex reversal, gonadal | Change from one sex to another with regard to gonadal development; may be induced or occurs naturally in some invertebrates. (12 Dec 1998) |
| bladder neoplasms | Cancers or tumours of the bladder. The majority of bladder neoplasms are of the transitional cell variety and are usually papillary and multicentric. (12 Dec 1998) |
| bone marrow neoplasms | Neoplasms located in the bone marrow. They are differentiated from neoplasms composed of bone marrow cells, such as myeloma. most bone marrow neoplasms are metastatic. (12 Dec 1998) |
| breast neoplasms, male | Any neoplasms of the male breast. These occur infrequently in males in developed countries, the incidence being about 1% of that in females. Two-thirds of patients present with intraductal carcinoma. The average age of onset is 60 years for men. Orchiectomy was the standard treatment but it has been replaced by tamoxifen as the initial therapy since oestrogen-receptor-positive tumours are predominant in males. Orchiectomy and mastectomy may be used if initial drug therapy is not successful. The prognosis is worse than that for females. (12 Dec 1998) |
| vascular neoplasms | <oncology> Neoplasms located in vascular tissue or specific veins. They are differentiated from neoplasms, vascular tissue which are neoplasms composed of vascular tissue, such as angiofibroma or haemangioma. (12 Dec 1998) |
| pancreatic cystic neoplasms | <radiology> Microcystic adenoma, glycogen, benign, mucinous cystic neoplasm, macrocystic adenoma, cystadenoma/cystadenocarcinoma, mucin, pre-malignant, Both occur more commonly in women, peak in middle age (12 Dec 1998) |
| pancreatic neoplasms | <radiology> Adenocarcinoma, most common, usually in pancreatic head, nasty (1-2% survival at 1 yr!), cystic neoplasms, slow-growing, more common in women, isleT-cell tumours, soft-tissue tumours (rare), metastases (breast, lung, melanoma, stomach, colon) (12 Dec 1998) |
| mammary neoplasms | Tumours of the mammary gland. Their occurrence is uncommon with the exception of the female dog, in which they account for 25% of all neoplasms. (12 Dec 1998) |