| myelinated nerve fibre | An axon enveloped by a myelin sheath formed by oligodendroglia cells (in brain and spinal cord) or Schwann cells (in peripheral nerves). Synonym: medullated nerve fibre. (05 Mar 2000) |
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| myelination | The acquisition, development, or formation of a myelin sheath around a nerve fibre. Synonym: medullation, myelinization, myelinogenesis. (05 Mar 2000) |
| myelinic | Relating to myelin. (05 Mar 2000) |
| myelinic degeneration | Formation of myelin figures in the cytoplasm of cells, possibly by degradation or hydration of lipoprotein of self-digested organelles. (05 Mar 2000) |
| myelinization | The acquisition, development, or formation of a myelin sheath around a nerve fibre. Synonym: medullation, myelinization, myelinogenesis. (05 Mar 2000) |
| myelinoclasis | Destruction of myelin. See: demyelination, dysmyelination. Origin: myelin + G. Klasis, a breaking (05 Mar 2000) |
| myelinogenesis | Synonym: myelination. Origin: myelin + G. Genesis, production (05 Mar 2000) |
| myelinolysis | Dissolution of the myelin sheaths of nerve fibres. Origin: myelin + G. Lysis, dissolution (05 Mar 2000) |
| myelinolysis, central pontine | A form of massive demyelination of the pons occurring in malnutrition and alcoholism. The remarkable unsystematic dissolution of the sheaths of medullated fibres is its most certain feature. The lesion varies from only a few millimeters in diameter to almost the entire pons. The basic pathology is the destruction of the medullated sheaths throughout the lesions with relative sparing of the axis cylinders and intactness of the nerve cells of the pontine nuclei. Pathologically it is easily differentiated from infarction and the inflammatory demyelinations of multiple sclerosis and postinfectious encephalomyelitis. There does not appear to be a genetic, sex, or age factor. It is often, however, associated with some other serious disease, particularly chronic alcoholism. (adams & victor, principles of neurology, 2d ed, p720) (12 Dec 1998) |
| myelinopathy | A disorder affecting the myelin of peripheral nerve fibres, in contrast to one affecting axons (axonopathy). (05 Mar 2000) |