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myelin figure <cell biology> Structure that can form spontaneously when bilayer forming phospholipids (e.g. Egg lecithin) are added to water. They are reminiscent of the concentric layer structure of myelin.
(18 Nov 1997)
myelin p0 protein A protein that accounts for more than half of the peripheral nervous system myelin protein. The extracellular domain of this protein is believed to engage in adhesive interactions and thus hold the myelin membrane compact. It can behave as a homophilic adhesion molecule through interactions with its extracellular domains.
(12 Dec 1998)
myelin p2 protein A positively charged protein found in peripheral nervous system myelin. Sensitive immunological techniques have demonstrated that p2 is expressed in small amounts of central nervous system myelin sheaths of some species. It is an antigen for experimental allergic neuritis (neuritis, experimental allergic), the peripheral nervous system counterpart of experimental allergic encephalomyelitis.
(12 Dec 1998)
myelin protein A1 An important protein in the central nervous system.
Synonym: myelin protein A1.
(05 Mar 2000)
myelin proteins Proteins found in the myelin sheath. The major proteins of central nervous system myelin include: myelin proteolipid protein, myelin basic proteins, and myelin-associated glycoprotein. The major proteins of peripheral nervous system myelin include: myelin basic proteins (myelin p1 protein and myelin p2 protein), myelin p0 protein, and myelin-associated glycoprotein.
(12 Dec 1998)
myelin proteolipid protein A myelin protein that is the major component of the organic solvent extractable lipoprotein complexes of whole brain. It has been the subject of much study because of its unusual physical properties. It remains soluble in chloroform even after essentially all of its bound lipids have been removed.
(12 Dec 1998)
myelin sheath <anatomy, neurology> An insulating layer surrounding vertebrate peripheral neurons, that dramatically increases the speed of conduction. It is formed by specialised Schwann cells, that can wrap around neurons up to 50 times. The exposed areas are called nodes of Ranvier: they contain very high densities of sodium channels and action potentials jump from one node to the next, without involving the intermediate axon, a process known as saltatory conduction.
(18 Nov 1997)
myelin-associated glycoprotein A myelin protein found in the periaxonal membrane of both the central and peripheral nervous systems myelin sheaths. It has a structure that is similar to members of the ig superfamily that participate in cell adhesion.
(12 Dec 1998)
myelinated Having a myelin sheath.
Synonym: medullated.
(05 Mar 2000)
myelinated nerve <anatomy, nerve> A peripheral nerve whose axons are surrounded by layers of Schwann cell membranes that form the myelin sheath; also called medullated nerves.
(05 Mar 2000)
myelinated nerve fibre An axon enveloped by a myelin sheath formed by oligodendroglia cells (in brain and spinal cord) or Schwann cells (in peripheral nerves).
Synonym: medullated nerve fibre.
(05 Mar 2000)
myelination The acquisition, development, or formation of a myelin sheath around a nerve fibre.
Synonym: medullation, myelinization, myelinogenesis.
(05 Mar 2000)
myelinic Relating to myelin.
(05 Mar 2000)
myelinic degeneration Formation of myelin figures in the cytoplasm of cells, possibly by degradation or hydration of lipoprotein of self-digested organelles.
(05 Mar 2000)
myelinization The acquisition, development, or formation of a myelin sheath around a nerve fibre.
Synonym: medullation, myelinization, myelinogenesis.
(05 Mar 2000)
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