| Becker type muscular dystrophy | A muscular dystrophy that has many of the clinical features of Duchenne muscular dystrophy e.g., symmetrical involvement of first the pelvicrural muscles and then the pectoral girdle and proximal upper extremity muscles; pseudohypertrophy, especially of the calf muscles but with a much later age of onset (35-45 years), and more benign course. X-linked inheritance. (05 Mar 2000) |
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| Becker type tardive muscular dystrophy | Muscular dystrophy of late onset, often in the second or third decade, with relatively mild course; X-linked recessive inheritance; perhaps allelic with Duchenne's dystrophy, but milder and not a genetic lethal. Compare: Duchenne dystrophy. Synonym: Becker type tardive muscular dystrophy. (05 Mar 2000) |
| benign pseudohypertrophic muscular dystrophy | <neurology> An X-linked inherited disorder characterised by slowly progressive muscle weakness of the legs and pelvis. Other symptoms and findings include increased difficulty walking, intellectual retardation, fatigue and pseudohypertrophy of the calf muscles. (06 Aug 1998) |
| pelvofemoral muscular dystrophy | One of the less well-defined types of muscular dystrophy, probably heterogenous in nature. Onset usually in childhood or early adulthood and both sexes affected. Characterised by weakness and wasting, usually symmetrical, of the pelvic girdle muscles, the shoulder girdle muscles, or both, but not the facial muscles. Muscle pseudohypertrophy, heart involvement, and mental retardation are absent. Variable inheritance. Synonym: Leyden-Mobius muscular dystrophy, pelvofemoral muscular dystrophy, scapulohumeral muscular dystrophy. (05 Mar 2000) |
| childhood muscular dystrophy | The most common childhood muscular dystrophy, with onset usually before age 6. Characterised by symmetrical weakness and wasting of first the pelvic and crural muscles and then the pectoral and proximal upper extremity muscles; pseudohypertrophy of some muscles, especially the calf; heart involvement; sometimes mild mental retardation; progressive course and early death, usually in adolescence. X-linked inheritance (affects males and transmitted by females). Synonym: childhood muscular dystrophy, Duchenne's disease, pseudohypertrophic muscular dystrophy. (05 Mar 2000) |
| peroneal muscular atrophy | A group of three familial peripheral neuromuscular disorders, sharing the common feature of marked wasting of the more distal extremities, particularly the peroneal muscle groups, resulting in "stork legs." Two of the three subtypes are hereditary sensorimotor polyneuropathies, one demyelinating in type and the other axon loss in type, while the third subgroup is an anterior horn cell disorder. It usually involves the legs before the arms; pes cavus is often the first sign; autosomal dominant, autosomal recessive, and X-linked recessive types, with severity related to genetic type. Synonym: Charcot-Marie-Tooth disease. (05 Mar 2000) |
| circular layers of muscular tunics | The inner, circular layer of the smooth muscle of the muscular coat. Nomina Anatomica lists circular layers of muscular coats (stratum circulare tunicae muscularis...) of the following: 1) colon (... Coli ); 2) rectum (... Recti ); 3) small intestine (... Intestini tenuis ); 4) stomach (... Gastrici ). Synonym: stratum circulare tunicae muscularis gastricae, stratum circulare tunicae. (05 Mar 2000) |
| Werdnig-Hoffmann muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| muscular | <anatomy> Pertaining to or composing muscle. Origin: L. Muscularis (18 Nov 1997) |
| muscular artery | <anatomy, artery> An artery with a tunica media composed principally of circularly arranged smooth muscle. Synonym: distributing artery, medium artery. (05 Mar 2000) |
| muscular asthenopia | Asthenopia due to imbalance of the extrinsic ocular muscles. (05 Mar 2000) |
| muscular atrophy | Derangement in size and number of muscle fibres occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation. (12 Dec 1998) |
| muscular atrophy, spinal | Progressive degenerative disorder of motor neurons in the spinal cord, brainstem, and motor cortex, manifested clinically by muscular weakness, atrophy, and corticospinal tract signs in varying combinations. (12 Dec 1998) |
| muscular branches | Usually unnamed branches of nerves or vessels that supply the muscles. Synonym: rami musculares. (05 Mar 2000) |
| muscular coat | The muscular, usually middle, layer of a tubular structure; for most of the gastrointestinal tract, it consists of an outer longitudinal layer of muscle and an inner circular layer. Synonym: tunica muscularis. (05 Mar 2000) |