| transmissible murine colonic hyperplasia | A disease of young mice caused by the bacterium Citrobacter freundii and characterised by diarrhoea and mucosal hyperplasia of the descending colon. (05 Mar 2000) |
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| tumour viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) that cause solid tumours or leukaemias in mice. (12 Dec 1998) |
| typhus, murine | An acute infectious disease with fever, headache, and rash, all quite similar to, but milder than, epidemic typhus, caused by a related microoganism, rickettsia typhi (mooseri), transmitted to humans by rat fleas (xenopsylla cheopis). The animal reservoir includes rats, mice and other rodents. Murine typhus occurs sporadically worldwide but is more prevalent in congested rat-infested urban areas. Also known as endemic typhus, rat-flea typhus, and urban typhus of malaya. (12 Dec 1998) |
| Friend murine erythroleukaemia cell | <cell culture> Lines of mouse erythroblasts transformed by the Friend virus, that can be induced to differentiate terminally, producing haemoglobin, by various agents such as dimethyl sulphoxide. (18 Nov 1997) |
| Friend murine leukaemia virus | <virology> Murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell free extracts. Causes an unusual erythroblastosis like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. does not carry a host derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome. (18 Nov 1997) |
| leukaemia viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) producing leukaemia in mice. It is commonly induced by injecting filtrates of propagable tumours into newborn mice. The gross strain (gross virus) occurs spontaneously in inbred mice, but none of the other strains occurs naturally. (12 Dec 1998) |
| ambulatory plague | <infectious disease> A mild form of bubonic plague characterised by symptoms such as mild fever and lymphadenitis. Synonym: larval plague, parapestis, pestis ambulans, pestis minor. (05 Mar 2000) |
| black plague | In 14th-century Europe, the victims of the black plague had bleeding below the skin (subcutaneous haemorrhage) which made darkened ( blackened ) their bodies. Black plague can lead to black death characterised by gangrene of the fingers, toes, and nose. Black plague is caused by a bacterium (Yersinia pestis) which is transmitted to humans from infected rats by the oriental rat flea. (12 Dec 1998) |
| bubonic plague | <microbiology> This rare bacterial infection due to Yersinia pestis. It can cause painful, enlarged lymph nodes, fever, headache and prostration 2-7 days after a flea bite. May also cause pneumonia and sepsis. Transmitted in rodents and humans via an infected flea bite. The incubation period is 2-10 days. Yersinia infection is now rare in Western countries. Third world countries (for example India) can have epidemics of Yersinia. Treatment with antibiotics is necessary or most individuals will die. Even with antibiotic treatment the death rate is 5%. (15 Nov 1997) |
| rabbit plague | A virulent epidemic disease among laboratory rabbits caused by the rabbitpox virus, a member of the family Poxviridae; it does not apparently occur among wild rabbits. Synonym: rabbit plague. (05 Mar 2000) |
| Pahvant Valley plague | <infectious disease, microbiology> A rare infection of rabbits and rodents caused by the bacteria Francisella tularensis. Francisella tularensis is found in many animals (rabbits, rodents) and may be transmitted by direct contact or via insect bite (ticks and deer-fly). Humans can also contract the illness via the direct contact with the infected animal carcass (break in the skin). The illness is characterised by an ulcerative lesion at the site of the inoculation with regional lymph node swelling, pneumonia, fever, chills, headache, muscle pains and joint stiffness. Risk factors include an exposure to rabbits or recent tick bite. A vaccine is available for high risk workers. Treatment is with streptomycin or tetracycline. Tularaemia is fatal in 5% of untreated cases and in less than 1% of treated cases. Incidence: less than 200 cases per year (USA). Origin: Gr. Haima = blood (18 Jul 2002) |
| cattle plague | A viral disease of cloven-hoofed animals caused by morbillivirus. It may be acute, subacute, or chronic with the major lesions characterised by inflammation and ulceration of the entire digestive tract. (12 Dec 1998) |
| cattle plague virus | A species of morbillivirus causing cattle plague, a disease with high mortality. Sheep, goats, pigs, and other animals of the order artiodactyla can also be infected. (12 Dec 1998) |
| glandular plague | <microbiology> This rare bacterial infection due to Yersinia pestis. It can cause painful, enlarged lymph nodes, fever, headache and prostration 2-7 days after a flea bite. May also cause pneumonia and sepsis. Transmitted in rodents and humans via an infected flea bite. The incubation period is 2-10 days. Yersinia infection is now rare in Western countries. Third world countries (for example India) can have epidemics of Yersinia. Treatment with antibiotics is necessary or most individuals will die. Even with antibiotic treatment the death rate is 5%. (15 Nov 1997) |
| great plague | The Great Plague that swept London in 1665 was probably not really the plague but rather typhus. (12 Dec 1998) |
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