| tumour viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) that cause solid tumours or leukaemias in mice. (12 Dec 1998) |
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| typhus, murine | An acute infectious disease with fever, headache, and rash, all quite similar to, but milder than, epidemic typhus, caused by a related microoganism, rickettsia typhi (mooseri), transmitted to humans by rat fleas (xenopsylla cheopis). The animal reservoir includes rats, mice and other rodents. Murine typhus occurs sporadically worldwide but is more prevalent in congested rat-infested urban areas. Also known as endemic typhus, rat-flea typhus, and urban typhus of malaya. (12 Dec 1998) |
| Friend murine erythroleukaemia cell | <cell culture> Lines of mouse erythroblasts transformed by the Friend virus, that can be induced to differentiate terminally, producing haemoglobin, by various agents such as dimethyl sulphoxide. (18 Nov 1997) |
| Friend murine leukaemia virus | <virology> Murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell free extracts. Causes an unusual erythroblastosis like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. does not carry a host derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome. (18 Nov 1997) |
| leukaemia viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) producing leukaemia in mice. It is commonly induced by injecting filtrates of propagable tumours into newborn mice. The gross strain (gross virus) occurs spontaneously in inbred mice, but none of the other strains occurs naturally. (12 Dec 1998) |
| anaesthetic leprosy | A form of leprosy chiefly affecting the nerves, marked by hyperesthesia succeeded by anaesthesia, and by paralysis, ulceration, and various trophic disturbances, terminating in gangrene and mutilation. Synonym: Danielssen's disease, Danielssen-Boeck disease, dry leprosy, trophoneurotic leprosy. (05 Mar 2000) |
| articular leprosy | A late stage of anaesthetic leprosy. Synonym: mutilating leprosy. (05 Mar 2000) |
| borderline leprosy | A form of leprosy that is very unstable immunologically; the cutaneous nerves frequently present bacilli, but the lepromin test is usually negative; cutaneous lesions are comprised of flat bands or plaques. Synonym: dimorphous leprosy. (05 Mar 2000) |
| macular leprosy | A form of tuberculoid leprosy in which the lesions are small, hairless, and dry, and are erythematous in light skin and hypopigmented or copper-coloured in dark skin. (05 Mar 2000) |
| Malabar leprosy | <medicine> A disease of the skin, in which it become enormously thickened, and is rough, hard, and fissured, like an elephant's hide. Origin: L, fr. Gr, from, an elephant. Source: Websters Dictionary (01 Mar 1998) |
| rat leprosy | A slowly but progressively fatal form of leprosy occurring in rats, caused by Mycobacterium lepraemurium; it appears in two forms, glandular and musculocutaneous; causes induration, alopecia, and eventually ulceration. Synonym: mouse leprosy, murine leprosy. (05 Mar 2000) |
| mutilating leprosy | A late stage of anaesthetic leprosy. Synonym: mutilating leprosy. (05 Mar 2000) |
| histoid leprosy | A form of lepromatous leprosy with lesions microscopically resembling dermatofibromas or other spindle-celled tumours. (05 Mar 2000) |
| smooth leprosy | A benign, stable, and resistant form of the disease in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with clear-cut edges. Synonym: nodular leprosy, smooth leprosy. (05 Mar 2000) |
| nodular leprosy | A benign, stable, and resistant form of the disease in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with clear-cut edges. Synonym: nodular leprosy, smooth leprosy. (05 Mar 2000) |