| MCD | magnetic circular dichroism; mast-cell degranulation; mean cell diameter; mean of consecutive differ... |
|---|---|
| G6S | glucosamine-6-sulfatase |
| SIDS | sudden infant death syndrome; sulfo-iduronate sulfatase |
| STS | sequence tagged site; serologic test for syphilis; sodium tetradecyl sulfate; sodium thiosulfate; st... |
| IGD | idiopathic growth hormone deficiency; interglobal distance; isolated gonadotropin deficiency |
| N-acetylglucosamine-6-sulfatase | <enzyme> Deficient in sanfilippo syndrome type d Registry number: EC 3.1.6.14 Synonym: nagss, nagsase, glucosamine-6-sulfatase, n-acetylglucosamine-6-sulfate sulfatase (26 Jun 1999) |
|---|---|
| steryl-sulfatase | <enzyme> Arylsulfatases a and b hydrolyze nitrocatechol sulfate, but p-nitrophenyl sulfate is hydrolyzed only slightly by both enzymes; arylsulfatase c hydrolyzes both p-nitrophenyl sulfate and nitrocatechol sulfate, low substrate specificity located chiefly in microsomes; a and b are found in lysosomes; arylsulfatase a is cerebroside sulfatase and arylsulfatase b is chondro-4-sulfatase Registry number: EC 3.1.6.2 Synonym: arylsulfatase c, dehydroepiandrosterone sulfate sulfatase, steroid sulfatase, estrone sulfate sulfohydrolase, steroid sulphatase, cholesterol sulfatase, dhea sulfatase, 3 beta-hydroxysteroid sulfate sulfatase, estrone sulfate sulfatase, sterylsulfatase, steroid sulfohydrolase, cholesterol sulfate sulfatase, arylsulphatase c (26 Jun 1999) |
| N-sulfoglucosamine-3-sulfatase | <enzyme> Acts on n-acetylglucosamine-3-sulfate and n-sulfoglucosamine-3-sulfate Registry number: EC 3.1.6.15 Synonym: n-substituted glucosamine 3-o-sulphatase (26 Jun 1999) |
| sulfatase | 1. Trivial name for enzymes in EC group 3.1.6, the sulfuric ester hydrolases, which catalyze the hydrolysis of sulfuric esters (sulfates) to the corresponding alcohols plus inorganic sulfate; includes aryl-, sterol, glycol-, chondroitin, choline-, cellulose, cerebroside, and chondro-sulfatases. Synonym: arylsulfatase. (05 Mar 2000) |
| disulfoglucosamine-6-sulfatase | <enzyme> Acts on various n-substituted glucosamine-6-o-sulfates Registry number: EC 3.1.6.11 Synonym: disulphoglucosamine-6-sulphatase, glucosamine o,n-disulfate o-sulfohydrolase, glucosamine sulfatase, n-sulfoglucosamine-6-sulfatase (26 Jun 1999) |
| iduronate sulfatase | <enzyme> An enzyme that specifically cleaves the ester sulfate of iduronic acid, and is required for the desulfation of 2-sulfate iduronate residues in heparan sulfate. It is also required in dermatan sulfate degradation. Its deficiency has been demonstrated in Hunter's syndrome, which is characterised by an excess of dermatan sulfate and heparan sulfate. Chemical name: L-Iduronate-2-sulfate 2-sulfohydrolase Registry number: EC 3.1.6.13 (20 Sep 2002) |
| oligosaccharide 2-O-sulfatase | <enzyme> Hydrolyzes the 2-o-sulfate of the disaccharide 4-deoxy-2-o-sulfato-alpha-l-threo-hex-4-enopyranosyluronic acid-(1-4)-2-deoxy-2-sulfamido-6-o-sulfato-d-glucose from heparin Registry number: EC 3.1.6.- Synonym: flavobacterium heparinum 2-o-sulphatase, heparo-2-o-sulfatase (26 Jun 1999) |
| oligosaccharyl sulfatase | <enzyme> From keyhole limpet; hydrolyzes sulfate esters in asparagine-linked oligosaccharides preferentially to 4-nitrocatechol sulfate Registry number: EC 3.1.6.- (26 Jun 1999) |
| lactate-2-sulfate sulfatase | <enzyme> Shows no activity for (l)-isomer Registry number: EC 3.1.6.- Synonym: d-lactate-2-sulfate sulfatase, d-lactate-2-sulfatase (26 Jun 1999) |
| 3b-hydroxysteroid sulfate sulfatase | <enzyme> An enzyme, found in most mammalian tissues, that is capable of hydrolyzing the sulfate ester bonds of a variety of sulfated sterols; a deficiency of this enzyme will result in X-linked ichthyosis. (05 Mar 2000) |
| abortion, multiple | Couples who have had 2 or more miscarriages (spontaneous abortions) have about a 5% chance that one member of the couple is carrying a chromsome translocation responsible for the miscarriages. (12 Dec 1998) |
| advanced multiple-beam equalization radiography | A variant of scanning equalization radiography using several X-ray beams. (05 Mar 2000) |
| amyloidosis of multiple myeloma | Foci of amyloidosis in mesenchymal tissues of some persons with multiple myeloma; no direct relation between amyloid and Bence Jones protein is conclusively known. (05 Mar 2000) |
| cancer, multiple myeloma | A bone marrow cancer involving a type of white blood cell called a plasma (or myeloma) cell. The tumour cells can form a single collection (a plasmacytoma) or many tumours (multiple myeloma). Plasma cells are part of the immune system and make antibodies. Because patients have an excess of identical plasma cells, they have too much of one type of antibody. As myeloma cells increase in number, they damage and weaken the bones, causing pain and often fractures. When bones are damaged, calcium is released into the blood leading to hypercalcaemia (excess calcium in the blood) and that causes loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Myeloma cells prevent the bone marrow from forming normal plasma cells and other white blood cells important to the immune system so patients may not be able to fight infections. The cancer cells can also prevent the growth of new red blood cells, causing anaemia. Excess antibody proteins and calcium may prevent the kidneys from filtering and cleaning the blood properly Cancer, non-Hodgkin's lymphoma: A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| chromosomes in multiple miscarriages | Couples who have had more than one miscarriage (spontaneous abortion) have about a 5% chance that one member of the couple is carrying a chromsome translocation responsible for the miscarriages. (12 Dec 1998) |