| multiple cloning site | Region of a phage or plasmid vector that has been engineered to contain a series of restriction sites that are usually unique within the entire vector. This makes it particularly easy to insert or excise (subclone) DNA fragments. (18 Nov 1997) |
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| multiple drug resistant tuberculosis | A strain of TB that does not respond to two or more standard anti-TB drugs. MDR-TB usually occurs when treatment is interrupted thus allowing mutations in the organism to occur that confer drug resistance. (09 Oct 1997) |
| multiple ego states | Various psychological organizational state's reflecting different personas or life experiences. (05 Mar 2000) |
| multiple embolism | Embolism caused by the arrest of a number of small emboli. (05 Mar 2000) |
| multiple endocrine adenomatosis | The presence of functioning tumours in more than one endocrine gland, commonly the pancreatic islets and parathyroid glands, which may be associated with Zollinger-Ellison syndrome; dominant inheritance. Synonym: multiple endocrine adenomatosis. (05 Mar 2000) |
| multiple endocrine deficiency syndrome | <syndrome> Acquired deficiency of the function of several endocrine glands, usually on an auto-immune basis. Synonym: multiple glandular deficiency syndrome. (05 Mar 2000) |
| multiple endocrine neoplasia | (type I) This is a hereditary disorder in which two or more of the following glands: parathyroid, pancreas, pituitary, adrenals or thyroid develop hyperplasia or a tumour. (type II) This is a hereditary disorder in which two or more of the following glands: thyroid, adrenal or parathyroid, develop overgrowth (hyperplasia) or malignant cells (cancer). The underlying cause is genetic and a positive family history for this illness is a risk factor. Incidence: approximately 3 in 100,000 people in the general population. Origin: Gr. Plassein = to form (27 Sep 1997) |
| multiple endocrine neoplasia 1 | <radiology> Multiple endrocrine neoplasia syndrome three P's. Pituitary adenoma, 65% can develop Cushing's, acromegaly, prolactinoma, parathyroid hyperplasia / adenoma, 88% can develop hyper-PTH pancreatic isleT-cell tumour, gastrinoma (Z-E) most common, 50% of Z-E can develop MEN-1, inconstant features: bronchial/intestinal carcinoid, thyroid adenoma, adrenal cortical tumour, lipoma, thymoma tissue expression Primary hyperparathyroidism (90%), Gastrinoma (30%), Prolactinoma (15%), Other (10%). Synonym: Wermer syndrome (12 Dec 1998) |
| multiple endocrine neoplasia 2 | <radiology> Multiple endocrine neoplasia syndrome, medullary thyroid carcinoma, usually multifocal; metastasis to local nodes, lung, liver, usually calcify in liver, pheochromocytoma, almost always bilateral, parathyroid hyperplasia, may be secondary to calcitonin secreted by medullary thyroid carcinoma inconstant feature: adrenal cortical hyperplasia Synonym: Sipple syndrome (12 Dec 1998) |
| multiple endocrine neoplasia 3 | <radiology> Multiple endocrine neoplasia syndrome (type 2B, type 3), medullary thyroid carcinoma, pheochromocytoma, marfanoid habitus (Cf: Marfan syndrome), mucosal neuromas, neurofibromas, ganglioneuromatosis coli More info: MEN syndrome 2B Synonym: Schimke, marfanoid syndrome (12 Dec 1998) |
| multiple endocrine neoplasia type 1 | A rare syndrome characterised by hyperplasia and/or neoplasms of the pituitary, parathyroid glands, and pancreatic islets. Hyperparathyroidism occurs in 90% of the cases and is usually the first manifestation of the syndrome. The most frequent pancreatic manifestation is gastrinoma typically leading to zollinger-ellison syndrome. The appearance of this condition has been limited to the loss of allelic heterozygosity at the 11q13 locus on the long arm of chromosome 11. Patients overall exhibit long survival times. Chemotherapy is rare and surgical management is generally dependent on the genetic expression in individual patients. (12 Dec 1998) |
| multiple endocrine neoplasia type 2 | <syndrome> This is a hereditary disorder in which two or more of the following glands: thyroid, adrenal or parathyroid, develop overgrowth (hyperplasia) or malignant cells (cancer). The underlying cause is genetic and a positive family history for this illness is a risk factor. Incidence: approximately 3 in 100,000 people in the general population. (27 Sep 1997) |
| multiple endocrine neoplasia type 2a | A type of multiple endocrine neoplasia characterised by a virtually 100% incidence of medullary thyroid carcinoma, a 50% incidence of pheochromocytoma, and a lesser incidence of parathyroid adenomas associated with hyperparathyroidism. The condition is always transmitted through autosomal dominant inheritance. Genetic testing can identify individuals with the trait in early infancy. Treatment is usually excision of the enlarged parathyroid glands. (12 Dec 1998) |
| multiple endocrine neoplasia type 2b | A type of multiple endocrine neoplasia occurring as an isolated congenital presentation or as a distinct autosomal dominant disease. It is characterised by the 100% incidence of medullary thyroid carcinoma and frequent pheochromocytomas; patients seldom exhibit hyperparathyroidism. It is distinguished from men 2a by its characteristic physical appearance resulting from numerous neural defects including mucosal neuromas of the eyelids, lips, and tongue. The neural abnormalities also include widespread neurogangliomatosis of the gastrointestinal tract leading to abnormal gut motility. Treatment usually requires total thyroidectomy following evaluation for the presence of pheochromocytomas. (12 Dec 1998) |
| multiple epiphysial dysplasia | A dominantly inherited abnormality of epiphyses characterised by difficulty in walking, pain and stiffness of joints, stubby fingers, and often dwarfism of short-limb type; on X-ray examination, the epiphyses are mottled and irregular; ossification centres are late in appearance and may be multiple, but the vertebrae are normal. There is also an autosomal recessive form . Synonym: dysplasia epiphysialis multiplex. (05 Mar 2000) |
Synonyms : MEA 1, MEA I, MEN I, MEN1, Multiple Endocrine Neoplasia Type I, Multiple Endocrine Neoplasms Type 1, Neoplasms, Multiple Endocrine Type I
Synonyms : MEA 2a, MEA II, MEA IIa, MEN II, MEN IIa, MEN2a, Multiple Endocrine Neoplasia Type 2, Multiple Endocrine Neoplasms Type 2a
Synonyms : MEA 2b, MEA IIb, MEN III, MEN IIb, MEN2b, Mucosal Neuroma Syndrome, Multiple Endocrine Neoplasms Type 2b, Neuroma Syndrome, Mucosal
Synonyms : Multiple Myelomas, Myeloma, Multiple, Myeloma, Plasma Cell, Myelomas, Multiple, Myelomas, Plasma-Cell, Plasma-Cell Myeloma, Plasma-Cell Myelomas
Synonyms : Failure, Multiple Organ, Multiple Organ Failures
| multiple personality |
split personality: a relatively rare dissociative disorder in which the usual integrity of the personality breaks down and two or more independent personalities emerge
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| multiple sclerosis |
a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers
출처: wordnet.princeton.edu/perl/webwn
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| multiple regression |
a statistical technique that predicts values of one variable on the basis of two or more other variables
출처: wordnet.princeton.edu/perl/webwn
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| multipotent |
able to many things; "multipotent drugs"
출처: wordnet.princeton.edu/perl/webwn
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| multiplication |
an arithmetic operation that is the inverse of division; the product of two numbers is computed; "the multiplication of four by three gives twelve"; "four times three equals twelve" generation: the act of producing offspring or multiplying by such production a multiplicative increase; "repeated copying leads to a multiplication of errors"; "this multiplication of cells is a natural correlate of growth"
출처: wordnet.princeton.edu/perl/webwn
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| multip | a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers |
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| multip | a system of three or more stars associated by gravity |
| multip | voting in more than one place by the same person at the same election (illegal in U.S.) |
| multip | offering several alternative answers from which the correct one is to be chosen |
| multip | communicates two or more signals over a common channel |
| multip | having many parts or aspects |
| multip | many and varied |
| multip | an operation in which two or more activities are interleaved |
| multip | a device that can interleave two or more activities |
| multip | the number that is multiplied by the multiplier |
| multip | the act of producing offspring or multiplying by such production |
| multip | an arithmetic operation that is the inverse of division |