| lymphoma, small lymphocytic | A low-grade malignant lymphoma that may, in some cases, be considered histologically identical to chronic lymphocytic leukaemia (cll; leukaemia, lymphocytic, chronic). It is diffuse in pattern, representing the neoplastic proliferation of well-differentiated B-lymphocytes. In patients with immunoglobulin gammopathies, the lymphocytes may exhibit plasmacytoid characteristics. (12 Dec 1998) |
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| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |
| carcinoma, large cell | A tumour of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (12 Dec 1998) |
| large cell carcinoma | A group of lung cancers in which the cells are large and look abnormal. (12 Dec 1998) |
| mixed cell leukaemia | Term infrequently used as a designation for granulocytic leukaemia, thereby emphasizing the occurrence of different types of cells in the myeloid series (i.e., neutrophilic, eosinophilic, and basophilic granulocytes), in contrast to the comparatively monotonous pattern observed in lymphocytic and monocytic leukaemia. (05 Mar 2000) |
| adult T-cell lymphoma | <tumour> An acute or subacute disease associated with a human T-cell virus, with lymphadenopathy, hepatosplenomegaly, skin lesions, peripheral blood involvement, and hypercalcaemia. Synonym: adult T-cell leukaemia. (05 Mar 2000) |
| cutaneous T-cell lymphoma | <oncology, tumour> A type of non-Hodgkin's lymphoma that first appears on the skin. Synonym: mycosis fungoides. (13 Nov 1997) |
| human T-cell lymphoma/leukaemia virus | A group of viruses (subfamily Oncovirinae, family Retroviridae) that are lymphotropic with a selective affinity for the helper/inducer cell subset of T lymphocytes and that are associated with adult T-cell leukaemia and lymphoma. Synonym: human T-cell lymphotropic virus. (05 Mar 2000) |
| diffuse small cleaved cell lymphoma | <tumour> A diffuse poorly differentiated lymphocytic lymphoma; follicular centre cell lymphoma that lacks a follicular pattern; malignancy is of intermediate grade. (05 Mar 2000) |
| T-cell lymphoma | A cancer of the immune system that appears in the skin; also called mycosis fungoides. (12 Dec 1998) |
| follicular predominantly small cleaved cell lymphoma | <tumour> A B-cell lymphoma with nodular or diffuse lymph node or bone marrow involvement by large lymphoid cells. Synonym: follicular predominantly small cleaved cell lymphoma, nodular histiocytic lymphoma. (05 Mar 2000) |
| lymphoma, B-cell | A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (12 Dec 1998) |
| lymphoma, small-cell | A B-cell lymphoma presumably representing a tumour of interfollicular B-lymphocytes that may be functional. Those that are secrete identical immunoglobulin molecules. (12 Dec 1998) |
| lymphoma, small cleaved-cell, diffuse | An intermediate-grade malignant lymphoma in which the neoplastic cells (B-lymphocytes) exhibit variability in size, configuration, and degree of differentiation. The cells have distinctive nuclei, irregular in shape, with marked indentations and angularity. (12 Dec 1998) |
| lymphoma, small cleaved-cell, follicular | A low-grade malignant lymphoma of predominantly follicular pattern. Follicles are of relatively uniform size and shape and the cells are usually somewhat larger than normal lymphocytes. Nuclei are irregular with prominent indentations and cytoplasm can rarely be identified. Cells exhibiting these characteristics are often called centrocytes. (12 Dec 1998) |